Product image of Opticrom Aqueous (Sodium Cromoglicate) supplied by GNH India

Opticrom Aqueous

Active Ingredient:
Sodium Cromoglicate
Origin:
EU

Opticrom Aqueous (Sodium Cromoglicate)

Sodium cromoglicate, the active ingredient in Opticrom Aqueous, is a mast cell stabilizer presented as an aqueous ophthalmic solution for ocular use. It helps control allergic inflammation of the eye, particularly in patients with allergic conjunctivitis and vernal keratoconjunctivitis.

GNH India supplies Opticrom Aqueous as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution, including temperature‑controlled shipping where required, and comprehensive regulatory support for importers.

Manufacturer / TM Owner

Aspire Pharma Limited

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Indications & Clinical Uses

Opticrom Aqueous, a mast cell stabilizer, is used to manage ocular allergic conditions by preventing mediator release.

  • Allergic conjunctivitis: reduces ocular itching, redness and tearing associated with seasonal allergens.
  • Vernal keratoconjunctivitis: helps control chronic inflammation and photophobia in patients with this severe allergic eye disease.
  • Seasonal allergic conjunctivitis: alleviates symptoms during pollen seasons by stabilizing mast cells in the conjunctiva.

How It Works

  • Sodium cromoglicate acts by binding to mast cell membranes and inhibiting calcium‑dependent degranulation. This prevents the release of histamine, leukotrienes, prostaglandins and other inflammatory mediators that cause ocular itching, redness and swelling. By stabilizing mast cells, the drug reduces the cascade of allergic inflammation in the conjunctiva and cornea.

Side Effects

Adverse reactions are generally mild and localized to the eye.

Common Side Effects

  • Burning or stinging sensation on instillation.
  • Transient blurred vision.
  • Mild eye irritation or foreign‑body sensation.
  • Temporary conjunctival hyperemia.
  • Tearing or increased lacrimation.
  • Mild eyelid edema.

Serious or Rare Side Effects

  • Allergic contact dermatitis of the eyelid or peri‑ocular skin.
  • Severe eye pain or persistent redness.
  • Vision loss or sudden visual acuity changes.
  • Corneal ulceration or keratitis.
  • Anaphylactic reaction (extremely rare).

Precautions & Warnings

Before prescribing Opticrom Aqueous, clinicians should consider the following safety measures.

  • Assess patient history: verify no known hypersensitivity to sodium cromoglicate or excipients.
  • Evaluate ocular surface: avoid use in active eye infections or severe corneal disease.
  • Contact lens wearers: remove lenses before instillation and wait several minutes before reinserting.
  • Concomitant ocular medications: monitor for additive irritation when used with other drops.
  • Pediatric use: safety and efficacy have not been established in children under the recommended age.
  • Store at below 25°C: keep in the original container, protect from light and moisture.

Avoid Interactions

Opticrom Aqueous may interact with other ophthalmic agents, requiring careful management.

Major Interactions (Avoid)

  • Concurrent use with other mast cell stabilizers: may increase local irritation.
  • Simultaneous administration with preservative‑containing drops: risk of cumulative ocular surface toxicity.

Moderate Interactions (Monitor Closely)

  • Systemic antihistamines: may reduce tear production, potentially worsening dryness.
  • Topical corticosteroids: monitor for additive immunosuppression.
  • Contact lens solutions: ensure compatibility to avoid lens discoloration or discomfort.

Frequently Asked Questions

Opticrom Aqueous is an ophthalmic solution containing sodium cromoglicate, a mast cell stabilizer used to treat allergic eye conditions such as allergic conjunctivitis and vernal keratoconjunctivitis. It works by preventing the release of inflammatory mediators that cause itching, redness and tearing.

Sodium cromoglicate binds to mast cell membranes in the conjunctiva and inhibits calcium‑dependent degranulation. By blocking the release of histamine, leukotrienes and prostaglandins, it reduces the allergic inflammatory response, thereby relieving ocular symptoms associated with allergy.

The dosing regimen for Opticrom Aqueous is determined by the prescribing clinician based on the severity of the allergic condition, patient age and response to therapy. Typical instructions involve one to two drops per eye at the recommended frequency, but the exact schedule should follow the prescriber’s order.

Safety data for sodium cromoglicate ophthalmic use in pregnancy or lactation are limited. Clinicians should weigh the potential benefits against any unknown risks and consider alternative treatments if appropriate. Pregnant or nursing patients should discuss use with their healthcare provider.

To request Opticrom Aqueous, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Opticrom Aqueous belongs to the mast cell stabilizer class, which prevents mediator release, whereas many eye allergy drops are antihistamines that block histamine receptors after release. Mast cell stabilizers can provide longer‑term control of inflammation, while antihistamines often give rapid symptom relief. The choice depends on clinical needs and physician preference.

The product should be stored at temperatures below 25 °C, protected from light and moisture, and kept in its original container. Do not freeze the solution. Once opened, follow the label’s recommended period‑after‑opening (PAO) and discard any remaining drops if contamination is suspected.

Opticrom Aqueous is applied as an eye drop. The patient should wash hands, tilt the head back, pull down the lower eyelid to form a pocket, and instill the prescribed number of drops. The eye should be closed gently for a few seconds to allow absorption, and contact lenses should be removed before administration.

Serious adverse events are rare but may include allergic contact dermatitis of the eyelid, severe eye pain, sudden loss of visual acuity, corneal ulceration or anaphylaxis. Patients should seek immediate medical attention if they experience any of these symptoms after using the drops.

Opticrom Aqueous should be avoided in individuals with known hypersensitivity to sodium cromoglicate or any formulation excipients. It is also contraindicated in eyes with active infection, severe corneal disease, or when the patient is unable to follow proper administration techniques.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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