Optimon Plus (Lisinopril Dihydrate, Hydrochlorothiazide)

Lisinopril is an angiotensin‑converting enzyme (ACE) inhibitor. It blocks the conversion of angiotensin I to the potent vasoconstrictor angiotensin II, leading to relaxation of blood vessels, reduced aldosterone secretion, and lower systemic vascular resistance, which helps lower blood pressure.

The specific dose of Optimon Plus is determined by the prescribing clinician based on the patient’s blood‑pressure goals, renal function, and other individual factors. Dosage adjustments are made according to clinical response and tolerability.

Optimon Plus is contraindicated in the second and third trimesters of pregnancy because ACE inhibitors can cause fetal injury. Safety during breastfeeding has not been established; therefore, it should be used only if the potential benefit justifies the potential risk to the infant.

To order Optimon Plus, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Optimon Plus combines an ACE inhibitor with a thiazide diuretic, offering dual mechanisms—vasodilation and diuresis—in a single tablet. This can improve adherence compared with taking two separate agents. Alternatives may include ARB‑diuretic combos or monotherapy, but the choice depends on patient tolerance, comorbidities and physician preference.

Optimon Plus should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original blister pack or container, protect them from moisture and direct sunlight, and ensure they are out of reach of children.

Optimon Plus is taken orally, usually once daily, with or without food as directed by the prescriber. Swallow the tablet whole with a full glass of water; do not crush or chew it unless specifically instructed.

The most serious risks include angioedema (swelling of the face, lips, tongue, or airway), severe hypotension, acute kidney injury, and hyperkalemia. Patients should seek immediate medical attention if they experience swelling, difficulty breathing, sudden dizziness, or a marked drop in urine output.

Optimon Plus should not be used by individuals with a known hypersensitivity to lisinopril, hydrochlorothiazide, or any component of the formulation. It is also contraindicated in patients with hereditary or idiopathic angioedema, severe renal impairment, or in the second and third trimesters of pregnancy.