Product image of Optiray (Ioversol) supplied by GNH India

Optiray

Active Ingredient:
Ioversol
Origin:
EU

Optiray (Ioversol)

Ioversol, the active ingredient in Optiray, is an iodinated contrast media presented as an injectable solution for intraarterial, intravenous use. It provides radiodensity for imaging procedures and is used in patients undergoing X‑ray, CT, and angiographic studies.

GNH India supplies Optiray as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Guerbet

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Indications & Clinical Uses

Optiray (ioversol) is an iodinated contrast agent used to enhance radiographic visualization of vascular and organ structures.

  • CT imaging: improves contrast between tissues for clearer diagnostic images.
  • Angiography: delineates blood vessels to aid in vascular assessment.
  • X‑ray studies: enhances visualization of anatomical details during conventional radiography.

How It Works

  • Ioversol contains iodine atoms that strongly absorb X‑ray photons. When injected intravenously or intra‑arterially, the iodine increases the radiodensity of blood and extracellular fluid, creating a contrast between vascular or tissue structures and surrounding background on X‑ray‑based imaging modalities such as CT and angiography.

Side Effects

Adverse reactions may occur following administration of ioversol. Patients should be monitored for both common and serious events.

Common Side Effects

  • Warm sensation or flushing at the injection site.
  • Metallic taste in the mouth.
  • Nausea or vomiting.
  • Mild headache.
  • Transient hypotension.
  • Injection site pain.

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis).
  • Contrast‑induced nephropathy or renal impairment.
  • Pulmonary edema.
  • Cardiac arrhythmia.
  • Seizures.
  • Severe hypotension or shock.

Precautions & Warnings

Prior to using Optiray, clinicians should consider several safety measures.

  • Renal function: assess kidney function and hydration status before administration.
  • Allergy history: screen for previous reactions to iodine‑containing contrast agents.
  • Thyroid disease: use with caution in patients with hyperthyroidism or thyroid disorders.
  • Pregnancy: category B; employ only when diagnostic benefit outweighs potential risk.
  • Concomitant nephrotoxic drugs: monitor closely if patient is receiving aminoglycosides, NSAIDs, or similar agents.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Ioversol may interact with other medications, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Iodine‑containing drugs (e.g., amiodarone): increase risk of thyroid dysfunction.
  • Nephrotoxic agents (e.g., aminoglycosides, high‑dose NSAIDs): heightened risk of renal injury.
  • Diuretics: may exacerbate volume depletion and affect renal perfusion.

Moderate Interactions (Monitor Closely)

  • Metformin: risk of lactic acidosis in patients with impaired renal function.
  • ACE inhibitors or ARBs: monitor renal function and blood pressure.
  • Beta‑blockers: may mask signs of hypotension after contrast administration.

Frequently Asked Questions

Optiray contains ioversol, an iodinated contrast agent that enhances the visibility of blood vessels, organs, and tissues during X‑ray‑based imaging procedures such as computed tomography (CT), conventional radiography, and angiography. It helps radiologists obtain clearer diagnostic images.

Ioversol’s iodine atoms absorb X‑ray photons strongly, increasing the radiodensity of the blood and extracellular fluid where it is distributed. This creates a contrast between enhanced structures and surrounding tissues, allowing imaging systems to differentiate anatomical details more clearly.

The dose of Optiray is individualized by the prescribing physician based on the specific imaging study, patient weight, renal function, and the required level of contrast enhancement. The healthcare professional determines the appropriate volume and concentration for each case.

Optiray is classified as pregnancy category B, indicating that animal studies have not shown risk to the fetus and there are no adequate human studies. It should be used only if the diagnostic benefit justifies potential risk. Limited data are available for breastfeeding, so caution is advised.

To order Optiray, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Optiray (ioversol) is a non‑ionic, low‑osmolality iodinated contrast medium, offering a favorable safety profile compared with older high‑osmolality agents. It provides comparable image quality to other low‑osmolality agents such as iohexol or iopamidol, while generally causing fewer adverse reactions.

Optiray should be stored at 2‑8 °C in a refrigerator, protected from light. Do not freeze the solution or shake it vigorously. Keep the vial in its original packaging until use to maintain sterility and stability.

Optiray is administered as an injectable solution via intravenous or intra‑arterial injection, depending on the imaging protocol. The injection is typically performed by a trained radiology or nursing professional using a power injector or manual bolus, following aseptic technique.

The most serious risks include severe allergic reactions (anaphylaxis), contrast‑induced nephropathy leading to renal impairment, and cardiovascular events such as severe hypotension or arrhythmias. Immediate medical attention is required if any of these reactions occur.

Optiray should be avoided in patients with a known hypersensitivity to ioversol or other iodinated contrast agents, those with uncontrolled severe renal insufficiency, and individuals with a history of severe thyroid disorders related to iodine exposure. Clinical judgment is essential for each patient.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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