Product image of Optiray (Ioversol) supplied by GNH India

Optiray

Active Ingredient:
Ioversol
Origin:
EU

Optiray (Ioversol)

Ioversol, the active ingredient in Optiray, is a iodinated contrast media presented as a solution for injection for intraarterial and intravenous use. It provides radiopaque contrast for diagnostic imaging procedures such as angiography, CT, urography and venography.

GNH India supplies Optiray as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑compliant documentation for global distribution. Customers receive dedicated technical support and reliable logistics tailored to each market's requirements.

Manufacturer / TM Owner

Guerbet

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Indications & Clinical Uses

Optiray (ioversol) is an iodinated contrast agent used in radiographic imaging procedures.

  • Angiography: Enhances vascular visualization to aid diagnosis and interventional planning.
  • Computed tomography (CT) imaging: Improves tissue differentiation and lesion detection.
  • Urography: Highlights urinary tract structures for functional assessment.
  • Venography: Provides clear delineation of venous anatomy for evaluation.

How It Works

  • Ioversol contains a high density of iodine atoms that absorb X‑ray photons, increasing attenuation of the X‑ray beam in the vascular and extracellular compartments. After intravenous or intra‑arterial administration, the solution distributes rapidly throughout the bloodstream, creating a temporary radiopaque contrast that delineates anatomical structures during imaging studies.

Side Effects

Adverse reactions to Optiray may vary in frequency and severity.

Common Side Effects

  • Warm sensation: Transient feeling of heat during injection.
  • Nausea: Mild gastrointestinal upset occurring shortly after administration.
  • Mild urticaria: Small, transient skin wheals without systemic involvement.

Serious or Rare Side Effects

  • Anaphylaxis: Severe allergic reaction requiring immediate medical intervention.
  • Acute kidney injury: Deterioration of renal function, especially in patients with pre‑existing impairment.
  • Severe hypotension: Marked drop in blood pressure that may necessitate supportive care.

Precautions & Warnings

Before using Optiray, clinicians should consider several safety measures.

  • Renal function assessment: Evaluate serum creatinine and eGFR to identify patients at risk of contrast‑induced nephropathy.
  • Iodine allergy screening: Verify history of hypersensitivity to iodine‑containing agents.
  • Dose minimisation: Use the lowest effective volume for the intended imaging study.
  • Vital sign monitoring: Observe blood pressure and heart rate during and after injection.
  • Thyroid disease caution: Avoid in patients with uncontrolled hyperthyroidism or thyroid storm.
  • Store at ambient temperature: Keep in original container, protect from moisture and direct light.

Avoid Interactions

Optiray may interact with other agents that affect renal function or iodine handling.

Major Interactions (Avoid)

  • Concurrent iodinated contrast agents: Increases cumulative iodine load and risk of toxicity.
  • High‑dose iodine‑containing medications (e.g., amiodarone): May potentiate allergic reactions.
  • Radiopharmaceuticals relying on iodine uptake: Interferes with diagnostic accuracy.

Moderate Interactions (Monitor Closely)

  • Diuretics: Heighten risk of volume depletion and renal impairment.
  • Nephrotoxic antibiotics (e.g., aminoglycosides): May exacerbate kidney injury.
  • ACE inhibitors or ARBs: Potentially alter renal haemodynamics; monitor renal function.

Frequently Asked Questions

Optiray is an iodinated contrast medium used to enhance the visibility of blood vessels and organ structures during diagnostic imaging procedures such as angiography, computed tomography (CT), urography, and venography. It provides temporary radiopacity that helps radiologists identify anatomical details and pathological changes.

Ioversol contains a high concentration of iodine atoms, which strongly absorb X‑ray photons. When injected intravenously or intra‑arterially, it distributes throughout the vascular and extracellular spaces, increasing X‑ray attenuation in the targeted area. This creates a clear contrast between blood‑filled structures and surrounding tissues on the imaging scan.

The dose of Optiray is determined by the prescribing physician based on the specific imaging study, patient size, renal function, and clinical protocol. Healthcare professionals calculate the appropriate volume and concentration to achieve optimal image quality while minimizing potential risks.

The safety of Optiray in pregnancy and lactation has not been fully established. It should only be used when the diagnostic benefit outweighs potential risks to the fetus or infant, and after careful consideration by the treating physician. Consultation with obstetric and neonatal specialists is recommended.

To order Optiray, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Optiray (ioversol) is a non‑ionic, low‑osmolality iodinated contrast medium, offering a favorable safety profile compared with older high‑osmolality agents. Compared with other low‑osmolality agents, it provides similar image quality while potentially reducing the incidence of warmth sensations and mild adverse reactions.

Optiray should be stored at ambient temperature, below 25 °C, in its original packaging. Protect the solution from moisture, direct sunlight, and extreme temperature fluctuations. Do not freeze the product, and ensure the container is sealed to maintain sterility until use.

Optiray is administered as a sterile solution for injection via the intravenous or intra‑arterial route. The injection is performed by qualified healthcare personnel using aseptic technique, typically through a peripheral or central venous catheter, and the rate of administration is adjusted according to the imaging protocol.

The most serious risks include severe allergic reactions such as anaphylaxis, acute kidney injury (contrast‑induced nephropathy), and profound hypotension. Patients with known iodine allergy, impaired renal function, or uncontrolled thyroid disease require careful assessment before receiving Optiray.

Optiray is contraindicated in patients with a documented severe hypersensitivity to ioversol or any iodinated contrast agent, those with uncontrolled hyperthyroidism or thyroid storm, and individuals with severe renal impairment where the risk of contrast‑induced nephropathy outweighs diagnostic benefit.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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