Product image of Optrex Infected Eye Drops (Chloramphenicol) supplied by GNH India

Optrex Infected Eye Drops

Active Ingredient:
Chloramphenicol
Origin:
EU

Optrex Infected Eye Drops (Chloramphenicol)

Chloramphenicol, the active ingredient in Optrex Infected Eye Drops, is an antibiotic presented as an ophthalmic solution for ocular use. It targets bacterial infections of the eye, reducing symptoms such as redness, discharge, and swelling, and is employed in patients with bacterial conjunctivitis and other infected ocular conditions, including blepharitis and keratitis.

GNH India supplies Optrex Infected Eye Drops as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with a focus on quality assurance and regulatory compliance.

Manufacturer / TM Owner

Optrex Ltd.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Optrex Infected Eye Drops, a chloramphenicol‑based ophthalmic antibiotic, is indicated for bacterial infections of the ocular surface and related structures.
  • Bacterial conjunctivitis: reduces bacterial load, alleviating redness, discharge and discomfort.
  • Blepharitis (infected eyelid margin): helps clear bacterial infection and associated inflammation.
  • Keratitis (bacterial corneal infection): assists in controlling infection and preserving visual acuity.
  • Stye (hordeolum): treats bacterial infection of the eyelid gland, reducing swelling and pain.
  • Post‑surgical eye infection: prevents or treats bacterial contamination following ocular procedures.

How It Works

  • Chloramphenicol exerts its antibacterial effect by binding to the 50S subunit of bacterial ribosomes, inhibiting the peptidyl transferase activity required for protein synthesis. This blockade prevents the formation of essential bacterial proteins, resulting in a bacteriostatic action that limits bacterial replication in the ocular tissues. The drug penetrates the corneal epithelium, achieving therapeutic concentrations in the conjunctiva and tear film, thereby sustaining its antimicrobial activity throughout the treatment period.

Side Effects

Chloramphenicol eye drops may cause local and, rarely, systemic adverse reactions.

Common Side Effects

  • Eye irritation or burning
  • Stinging sensation on instillation
  • Transient blurred vision
  • Increased tearing

Serious or Rare Side Effects

  • Allergic reactions such as angioedema or contact dermatitis
  • Severe eye pain or worsening vision
  • Systemic bone‑marrow suppression (aplastic anemia) – extremely rare

Precautions & Warnings

When using Optrex Infected Eye Drops, several precautions should be observed to ensure safety and effectiveness.

  • Pregnancy: Category C – use only if the potential benefit justifies the potential risk to the fetus.
  • Breastfeeding: Caution advised; chloramphenicol may be excreted in breast milk.
  • Contact lens wearers: Remove lenses before instillation and wait at least 15 minutes before reinserting.
  • Known hypersensitivity: Do not use if the patient has a documented allergy to chloramphenicol or other phenicol antibiotics.
  • Prolonged use: Limit duration to the prescribed period to reduce risk of systemic absorption and bone‑marrow effects.
  • Store at room temperature: Keep in the original container, protect from light and moisture.

Avoid Interactions

Chloramphenicol can interact with certain systemic and topical agents; awareness of these interactions helps avoid adverse outcomes.

Major Interactions (Avoid)

  • Systemic chloramphenicol: concurrent use may increase the risk of bone‑marrow toxicity.
  • Monoamine oxidase inhibitors (MAOIs): may potentiate rare systemic side effects.

Moderate Interactions (Monitor Closely)

  • Topical corticosteroids: may mask signs of infection, requiring careful monitoring.
  • Other ophthalmic antibiotics: concurrent use can lead to antagonistic effects or increased irritation.
  • Alcohol: although not a direct ocular interaction, systemic absorption combined with alcohol may enhance central nervous system effects.

Frequently Asked Questions

Optrex Infected Eye Drops is a chloramphenicol‑containing ophthalmic solution indicated for the treatment of bacterial eye infections such as conjunctivitis, blepharitis, keratitis, styes and post‑surgical ocular infections. It works by reducing bacterial load, helping to relieve redness, discharge, swelling and discomfort associated with these conditions.

Chloramphenicol inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, blocking the peptidyl transferase step essential for forming new proteins. This bacteriostatic action halts bacterial replication in the ocular tissues, allowing the immune system to clear the infection while minimizing inflammation.

The dosing regimen for Optrex Infected Eye Drops is determined by the prescribing healthcare professional based on the severity of the infection, patient age and response to therapy. Typically, a few drops are instilled into the affected eye(s) at prescribed intervals, and the exact schedule should be followed as directed by the prescriber.

Chloramphenicol is classified as Pregnancy Category C, meaning it should only be used when the potential benefit outweighs any possible risk to the fetus. It can be excreted in breast milk, so caution is advised for nursing mothers. The prescriber will evaluate the risk‑benefit profile before recommending use in these populations.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Optrex Infected Eye Drops (chloramphenicol) offers a broad spectrum of activity against many Gram‑positive and Gram‑negative ocular pathogens and is well‑tolerated when used short‑term. Alternatives such as tobramycin or fusidic acid may have a narrower spectrum or different resistance profiles. Choice of therapy depends on local antibiograms, patient tolerance and prescriber preference.

The product should be stored at room temperature, away from direct sunlight and moisture. Keep the bottle tightly closed in its original packaging until use. Do not freeze the drops, and discard any solution that appears discolored or cloudy after the labeled expiry date.

Before instillation, wash hands thoroughly and avoid touching the tip of the bottle. Tilt the head back, gently pull down the lower eyelid to form a pocket, and place the prescribed number of drops into the conjunctival sac. Close the eye gently for a few seconds, then repeat for the other eye if directed. Do not rinse the eye immediately after dosing.

While most reactions are mild, serious adverse events can include severe allergic responses such as angioedema or contact dermatitis, significant eye pain or worsening vision, and, very rarely, systemic bone‑marrow suppression leading to aplastic anemia. Patients should seek immediate medical attention if they experience any of these severe symptoms.

Optrex Infected Eye Drops should be avoided in individuals with a known hypersensitivity to chloramphenicol or other phenicol antibiotics. It is also contraindicated in patients with pre‑existing bone‑marrow disorders and should be used with caution in pregnant or breastfeeding women, as well as in those requiring prolonged therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.