Oralair (Allergen Extract From Pollen Of Dactylis Glomerata, Anthoxanthum Odoratum, Lolium Perenne, Poa Prate)

Oralair is an allergen immunotherapy that addresses grass‑type pollen allergy pathways:

• Seasonal allergic rhinitis: reduces symptom severity and medication need during grass pollen season.
• Allergic conjunctivitis: alleviates eye irritation linked to grass pollen exposure.
• Mild to moderate asthma associated with grass pollen sensitivity: contributes to better airway control.
• Preventive allergy management: supports long‑term tolerance development to grass pollen allergens.
• Adjunct to pharmacologic therapy: enhances overall control when used with standard antihistamines or inhalers.
• Immunotherapy for children : provides a non‑injectable option for pediatric patients with grass pollen allergy.

• Oralair contains standardized extracts of grass pollen allergens that are administered sublingually. The extracts interact with oral mucosal immune cells, promoting a shift from IgE‑mediated hypersensitivity toward regulatory T‑cell responses and IgG4 production. This immunomodulatory effect gradually reduces the allergic inflammatory cascade triggered by grass pollen exposure.

Oralair may cause local and systemic reactions following sublingual exposure.

Common Side Effects

• Oral itching or mild irritation of the mouth.
• Throat discomfort or mild soreness.
• Ear or facial itching.
• Mild nasal congestion.
• Transient hoarseness.
• Mild gastrointestinal upset.

Serious or Rare Side Effects

• Systemic anaphylaxis requiring emergency treatment.
• Severe bronchospasm or asthma exacerbation.
• Laryngeal edema with breathing difficulty.
• Persistent high‑grade urticaria.
• Angio‑edema of the lips or tongue.
• Unexplained drop in blood pressure (hypotension).

Before initiating Oralair, consider the following precautions:

• Medical evaluation: confirm diagnosis of grass‑pollen allergy and suitability for sublingual immunotherapy.
• Asthma control: ensure asthma is well‑controlled before starting treatment.
• Concomitant medications: review antihistamines, beta‑agonists, or immunosuppressants for potential interaction.
• Pregnancy and lactation: discuss risks and benefits with a healthcare professional.
• Age restrictions: product is indicated for patients aged 5 years and older.
• Store at ambient temperature: keep in original packaging, protect from moisture and direct sunlight.

Oralair can interact with other medications that influence immune response or allergic reactivity.

Major Interactions (Avoid)

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