Product image of Oralair (Allergen Extract From Pollen Of Dactylis Glomerata, Anthoxanthum Odoratum, Lolium Perenne, Poa Prate) supplied by GNH India

Oralair

Active Ingredient:
Allergen Extract From Pollen Of Dactylis Glomerata, Anthoxanthum Odoratum, Lolium Perenne, Poa Prate
Origin:
EU

Oralair (Allergen Extract From Pollen Of Dactylis Glomerata, Anthoxanthum Odoratum, Lolium Perenne, Poa Prate)

Allergen Extract From Dactylis Glomerata, Anthoxanthum Odoratum, Lolium Perenne, Poa Prate, the active ingredient in Oralair, is a allergen immunotherapy presented as a tablet for sublingual use. It treats grass‑pollen‑induced allergic rhinitis and related symptoms in children and adults.
GNH India supplies Oralair as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Stallergenes

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Indications & Clinical Uses

Oralair is used in allergen immunotherapy for grass‑pollen‑induced allergic rhinitis and related conditions.

  • Seasonal allergic rhinitis (hay fever): reduces nasal congestion, sneezing and itching during grass pollen season.
  • Allergic conjunctivitis: alleviates eye itching, redness and tearing caused by grass pollen exposure.
  • Grass‑pollen‑triggered bronchial asthma: may improve asthma control in sensitised patients.

How It Works

  • Oralair delivers standardized grass‑pollen extracts to the oral mucosa, where they are taken up by antigen‑presenting cells. Repeated exposure induces regulatory T‑cells and a shift from IgE‑mediated responses toward IgG4 production, promoting immune tolerance and reducing allergic inflammation upon natural pollen exposure.

Side Effects

Common Side Effects

  • Mouth itching: mild irritation of the oral mucosa.
  • Throat irritation: transient soreness after tablet placement.
  • Ear pruritus: occasional itching in the ear canal.
  • Mild oral swelling: slight enlargement of lips or tongue that resolves quickly.

Serious or Rare Side Effects

  • Anaphylaxis: severe, potentially life‑threatening allergic reaction.
  • Systemic allergic reaction: widespread hives, wheezing or hypotension.
  • Swelling of the tongue or throat: may compromise airway.
  • Persistent wheezing: ongoing respiratory difficulty requiring medical attention.

Precautions & Warnings

Oralair should be administered under medical supervision with attention to the following precautions.

  • Medical supervision: initiate treatment under the guidance of an allergist or qualified physician.
  • Age restrictions: approved for patients aged 5 years and older.
  • Concurrent immunotherapy: avoid using other allergen immunotherapy products simultaneously.
  • Pregnancy and lactation: discuss potential risks with a healthcare provider before use.
  • Store at ambient temperature below 25°C: keep in the original container, protect from moisture and light.

Avoid Interactions

Oralair may interact with other medications; consider the following.

Major Interactions (Avoid)

  • Beta‑blockers: can mask symptoms of anaphylaxis and complicate emergency treatment.
  • ACE inhibitors: may increase the risk of severe allergic reactions.

Moderate Interactions (Monitor Closely)

  • Antihistamines: may reduce local side effects but do not affect efficacy.
  • Corticosteroids: could alter the immune response to the immunotherapy.
  • Other sublingual immunotherapy products: risk of additive allergic reactions.

Frequently Asked Questions

Oralair is a sublingual immunotherapy tablet containing standardized grass‑pollen extracts. It is prescribed to reduce symptoms of allergic rhinitis, conjunctivitis and asthma that are triggered by grass pollen exposure in sensitised individuals.

The allergen extracts in Oralair are absorbed through the oral mucosa, where they stimulate regulatory immune pathways. This leads to a gradual shift from IgE‑driven allergy responses toward IgG4 production and increased regulatory T‑cell activity, fostering long‑term tolerance to grass pollen.

The dosing regimen for Oralair is individualized. A qualified healthcare professional determines the starting dose, escalation schedule and maintenance dose based on the patient’s age, sensitivity profile and clinical response.

Safety data for Oralair in pregnancy and lactation are limited. Women who are pregnant, planning pregnancy, or breastfeeding should discuss potential benefits and risks with their prescribing physician before starting treatment.

To request Oralair, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Oralair is a sublingual tablet, offering a needle‑free alternative to injectable grass‑pollen extracts. It provides comparable efficacy in symptom reduction while allowing self‑administration at home, which can improve patient convenience and adherence compared with traditional subcutaneous immunotherapy.

Oralair tablets should be stored at ambient temperature below 25 °C, in the original packaging, protected from moisture and direct sunlight. Keep the product out of reach of children and avoid exposing it to extreme heat or humidity.

The tablet is placed under the tongue and allowed to dissolve completely without swallowing or drinking for a few minutes. Patients should remain seated and avoid eating or drinking for at least 10 minutes after administration, following the prescriber’s instructions.

The most serious risks include systemic allergic reactions such as anaphylaxis, severe swelling of the tongue or throat, and persistent wheezing. Patients should be educated to recognize early signs of a severe reaction and seek immediate medical attention if they occur.

Oralair is contraindicated in individuals with a history of severe systemic reactions to grass‑pollen extracts, uncontrolled asthma, or those receiving beta‑blocker therapy without medical supervision. It should also be avoided in patients with active oral infections or severe dental disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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