Oraqix (Lidocaine, Prilocaine)

Oraqix is a topical local anesthetic used in the oral cavity to provide pain control for specific dental and oral procedures.

• Periodontal surgery: Provides localized anesthesia without the need for injectable anesthetic.
• Tooth extraction: Reduces discomfort during and after the procedure.
• Scaling and root planing: Improves patient comfort during deep cleaning.
• Oral mucosal biopsies: Facilitates painless removal of small tissue samples.
• Dental implant placement: Assists in achieving adequate so‑l­ t‑  l  un‑      un  ‑  ‑  un  ‑  ‑  un‑ un ‑ un‑un‑ un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un‑un​

• Oraqix contains lidocaine and prilocaine, which block voltage‑gated sodium channels on peripheral nerve membranes. This inhibition prevents the initiation and propagation of action potentials, producing a reversible loss of sensation in the applied area. The combined agents provide rapid onset of surface anesthesia suitable for intra‑oral procedures.

Oraqix may cause local and systemic reactions following application to the oral mucosa.

Common Side Effects

• Transient burning or stinging sensation at the application site.
• Mild oral mucosal irritation or erythema.
• Temporary numbness lasting longer than the procedure.
• Taste alteration or metallic taste.
• Mild headache.

Serious or Rare Side Effects

• Allergic reaction such as urticaria, angio‑edema, or anaphylaxis.
• Methemoglobinemia, particularly with excessive absorption.
• Cardiovascular changes including hypotension or arrhythmia.
• Central nervous system toxicity presenting as seizures.
• Persistent numbness beyond 24 hours.

Oraqix should be used only when the benefits outweigh potential risks, and clinicians should follow established dental protocols.

• Patient assessment: Verify no known allergy to amide‑type local anesthetics.
• Dosage control: Apply only the amount required for the targeted area.
• Medical history: Review for conditions that predispose to methemoglobinemia.
• Concurrent medications: Use caution with other sodium‑channel blockers.
• Monitoring: Observe the patient for signs of systemic toxicity during and after use.
• Store at ambient temperature: keep in original packaging, protect from moisture and direct sunlight.

Oraqix may interact with other medications that affect sodium channels or hemodynamic stability.

Major Interactions (Avoid)

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