Product image of Orbical-D3 (Colecalciferol, Calcium Carbonate) supplied by GNH India

Orbical-D3

Active Ingredient:
Colecalciferol, Calcium Carbonate
Origin:
EU

Orbical-D3 (Colecalciferol, Calcium Carbonate)

Colecalciferol, the active ingredient in Orbical-D3, is a vitamin D and calcium supplement presented as an oral tablet for oral use. It supports calcium absorption and bone mineralization in individuals with vitamin D or calcium deficiency, and helps maintain skeletal health.

GNH India supplies Orbical-D3 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The product complies with EU pharmacopeial standards and is distributed under strict quality assurance protocols. Its consistent batch-to-batch potency ensures reliable supplementation for diverse patient populations.

Manufacturer / TM Owner

Zwitter Pharmaceuticals Επε

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Orbical-D3 provides vitamin D3 and calcium to address conditions related to mineral deficiency and bone health.

  • Vitamin D deficiency: restores normal serum 25‑hydroxyvitamin D concentrations.
  • Calcium deficiency: contributes to maintaining adequate serum calcium levels.
  • Osteoporosis risk: supports bone mineral density and reduces bone turnover.
  • Secondary hyperparathyroidism: helps normalize parathyroid hormone levels.
  • Post‑menopausal bone loss: assists in preserving skeletal strength.

How It Works

  • Colecalciferol (vitamin D3) is converted in the liver to 25‑hydroxyvitamin D and then in the kidney to the active hormone 1,25‑dihydroxyvitamin D, which binds to vitamin D receptors in intestinal cells, up‑regulating calcium‑binding proteins and enhancing calcium absorption. Calcium carbonate supplies elemental calcium that is absorbed in the gastrointestinal tract, providing the mineral substrate needed for bone mineralization and other physiological functions.

Side Effects

Orbical-D3 may be associated with several adverse reactions, ranging from mild to serious.

Common Side Effects

  • Nausea
  • Constipation
  • Abdominal discomfort
  • Mild hypercalcemia
  • Headache
  • Dry mouth

Serious or Rare Side Effects

  • Severe hypercalcemia
  • Kidney stones
  • Allergic reactions such as rash or angioedema
  • Hypervitaminosis D
  • Cardiac arrhythmia

Precautions & Warnings

Before initiating Orbical-D3, consider the following precautions.

  • Assess baseline calcium and vitamin D levels: check serum concentrations prior to therapy.
  • Monitor renal function: especially important in patients with chronic kidney disease.
  • Avoid in hypercalcemia: contraindicated when serum calcium is elevated.
  • Caution in sarcoidosis or granulomatous disease: risk of excessive vitamin D activity.
  • Pregnancy and lactation: use only if clearly needed after risk‑benefit assessment.
  • Store at ambient temperature: keep in the original pack, protect from moisture and light.

Avoid Interactions

Orbical-D3 can interact with several medicines; awareness of the interaction level is essential.

Major Interactions (Avoid)

  • Thiazide diuretics: may precipitate hypercalcemia.
  • Excess vitamin A intake: increases risk of hypervitaminosis D.
  • Lithium therapy: can elevate calcium levels.

Moderate Interactions (Monitor Closely)

  • Orlistat: reduces absorption of fat‑soluble vitamins including vitamin D.
  • Anticonvulsants (e.g., phenytoin, phenobarbital): accelerate vitamin D metabolism.
  • Corticosteroids: may diminish calcium absorption and affect bone health.

Frequently Asked Questions

Orbical-D3 is a nutritional supplement that provides vitamin D3 (colecalciferol) and calcium carbonate. It is used to correct vitamin D and calcium deficiencies, support normal bone mineralization, and help maintain skeletal health in individuals at risk of osteoporosis or related conditions.

Colecalciferol is converted in the liver to 25‑hydroxyvitamin D and then in the kidney to the active form 1,25‑dihydroxyvitamin D. This active hormone binds to vitamin D receptors in the intestine, stimulating the production of calcium‑binding proteins that increase dietary calcium absorption, which is essential for bone formation and maintenance.

The appropriate dose of Orbical-D3 is determined by the prescribing healthcare professional based on the patient’s age, clinical condition, baseline vitamin D and calcium levels, and other individual factors. Patients should follow the dosage instructions provided by their prescriber and not adjust the dose on their own.

Orbical-D3 may be used during pregnancy or lactation only if the prescriber judges that the potential benefits outweigh any possible risks. Vitamin D and calcium are important for fetal bone development, but dosing should be individualized and monitored by a qualified healthcare provider.

To place an order, submit an enquiry on the Orbical-D3 product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and the necessary import documentation.

Unlike single‑ingredient vitamin D products, Orbical-D3 combines colecalciferol with calcium carbonate, offering both the hormonal stimulus for calcium absorption and the mineral itself. This dual formulation can be advantageous for patients who need simultaneous correction of vitamin D deficiency and calcium supplementation, reducing the need for separate products.

Orbical-D3 should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original packaging, protect them from moisture and direct light, and ensure the container is tightly closed to maintain product stability throughout its shelf life.

Orbical-D3 is taken orally, usually with food to enhance calcium absorption. The tablets should be swallowed whole with a glass of water. Patients should follow the specific administration instructions given by their healthcare professional.

The most serious risks include severe hypercalcemia, which can lead to kidney stones, cardiac arrhythmias, or neurological symptoms, and hypervitaminosis D, which may cause calcium overload and tissue calcification. Prompt medical attention is required if symptoms such as persistent vomiting, confusion, or severe abdominal pain occur.

Orbical-D3 is contraindicated in individuals with known hypersensitivity to any of its components, those with existing hypercalcemia, or patients with conditions such as sarcoidosis or other granulomatous diseases where vitamin D metabolism is altered. Consultation with a healthcare provider is essential before starting the supplement.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.