Orbimag 300 (Magnesium Oxide)

Orbimag 300 is a magnesium supplement that addresses conditions related to low magnesium levels or excess gastric acidity.

• Magnesium deficiency: helps restore normal serum magnesium concentrations.
• Hypomagnesemia: supports correction of clinically low magnesium values.
• Antacid therapy: neutralises excess stomach acid to relieve heartburn and dyspepsia.
• Occasional constipation: increases intestinal water content to facilitate bowel movements.

• Magnesium oxide dissociates in the gastrointestinal tract to release magnesium ions. These ions act as cofactors for numerous enzymatic reactions, contribute to neuromuscular function, and help regulate electrolyte balance. In the stomach, the basic oxide neutralises hydrogen ions, providing an antacid effect, while its osmotic activity draws water into the intestinal lumen, promoting laxation.

Orbimag 300 may cause unwanted physiological responses, most of which are mild and transient.

Common Side Effects

• Diarrhoea: loose stools occurring after ingestion.
• Abdominal cramping: mild to moderate stomach discomfort.
• Nausea: feeling of queasiness without vomiting.
• Flatulence: increased intestinal gas.
• Metallic taste: temporary alteration in mouthfeel.

Serious or Rare Side Effects

• Hypermagnesemia: elevated blood magnesium levels that may cause cardiac rhythm changes.
• Severe abdominal pain: persistent pain requiring medical evaluation.
• Allergic reaction: rash, itching, swelling, or difficulty breathing.
• Electrolyte imbalance: disturbances in calcium or potassium levels.
• Persistent vomiting: ongoing emesis that leads to dehydration.

Before using Orbimag 300, consider the following safety measures.

• Renal impairment: dose may need adjustment or avoidance in severe kidney disease.
• Cardiac conditions: monitor if patient has heart block or arrhythmias.
• Drug interactions: review concomitant medications that affect magnesium levels.
• Pregnancy and lactation: use only if clearly indicated by a healthcare professional.
• Storage: Store below 25°C: keep in the original container, protect from moisture and direct sunlight.

Orbimag 300 can affect the absorption or activity of several medicines. Review the following interaction categories.

Major Interactions (Avoid)

• Tetracycline antibiotics: reduced absorption of the antibiotic.
• Bisphosphonates: magnesium may decrease drug bioavailability.
• Potassium‑sparing diuretics: risk of additive hypermagnesemia.\nModerate Interactions (Monitor Closely):
• Calcium supplements: competition for intestinal absorption.
• Proton pump inhibitors: may alter magnesium homeostasis.
• ACE inhibitors: potential for enhanced hypotensive effect.