Orfadin 10 (Nitisinone Capsule) 10mg

Orfadin 10 capsule contains 10mg nitisinone, a medication used to manage hereditary tyrosinemia type 1. This rare metabolic disorder requires lifelong treatment to reduce harmful tyrosine levels. Store between 2-8°C and protect from light. Consult your pharmacist for handling guidance.

Strength

10mg

Pack Size

60s

Storage

2-8°

Manufacturer / TM Owner

Swedish Orphan Biovitrum

Select Quantity

Pack/s

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Indications & Clinical Uses

Nitisinone is prescribed to treat hereditary tyrosinemia type 1, a genetic condition affecting tyrosine metabolism. It helps prevent liver and kidney damage by lowering tyrosine levels in the blood. This medication is typically used alongside a low-protein diet to manage symptoms. What is nitisinone 10mg capsule used for in metabolic disorders?

Side Effects

Orfadin 10 capsules work by blocking an enzyme involved in tyrosine breakdown, which reduces toxic buildup in the body. Patients may notice improved energy levels and fewer metabolic crises over time. Regular blood tests help monitor tyrosine levels and adjust treatment as needed. Effects vary by individual and require consistent use.

Precautions & Warnings

Keep Orfadin 10 capsules refrigerated between 2-8°C and away from light. Handle with care to avoid moisture exposure. Do not crush or open capsules unless directed. Inform your healthcare provider about all medications and conditions before starting nitisinone. Store in original packaging to maintain stability.

Avoid Interactions

Nitisinone may interact with other drugs metabolized by the liver, including certain pain relievers and antibiotics. Avoid alcohol and grapefruit products while taking this medication. Some supplements, like vitamin C, may alter effectiveness. Always review your full medication list with a pharmacist before combining therapies.

Frequently Asked Questions

Orfadin 10 contains nitisinone and is used to treat hereditary tyrosinemia type 1, a rare metabolic disorder.

Store Orfadin 10 capsules refrigerated between 2-8°C and protect from light.

Do not crush or open Orfadin 10 capsules unless instructed by your healthcare provider.

Common effects may include nausea, itching, or temporary eye sensitivity. Report persistent issues to your doctor.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 29 Jul 2026

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