Product image of Orgovyx (Relugolix) supplied by GNH India

Orgovyx

Active Ingredient:
Relugolix
Origin:
EU

Orgovyx (Relugolix)

Relugolix, the active ingredient in Orgovyx, the active ingredient in Orgovyx, is a GnRH antagonist presented as a 120 mg tablet for oral use. It treats advanced prostate cancer and metastatic castration-sensitive prostate cancer in men. GNH India supplies Orgovyx as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, oncology centres, pharmacies and clinics worldwide.

GNH India supplies Orgovyx as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Accord Healthcare S.L.U.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Orgovyx is a GnRH antagonist used in the management of prostate‑related disease pathways.

  • Advanced prostate cancer: helps achieve medical castration levels of testosterone.
  • Metastatic castration‑sensitive prostate cancer: maintains low testosterone to slow disease progression.
  • Hormone‑sensitive prostate cancer: used as part of combination therapy to control tumor growth.

How It Works

  • Relugolix competitively blocks gonadotropin‑releasing hormone (GnRH) receptors in the pituitary gland, preventing the surge of luteinizing hormone and follicle‑stimulating hormone. This suppression reduces downstream production of testosterone, a key driver of prostate cancer cell proliferation, thereby exerting an androgen‑deprivation effect.

Side Effects

Orgovyx may cause a range of adverse reactions, most of which are manageable with monitoring.

Common Side Effects

  • Hot flashes
  • Fatigue
  • Decreased libido
  • Headache
  • Nausea
  • Diarrhea

Serious or Rare Side Effects

  • Cardiovascular events such as myocardial infarction
  • Severe hypertension
  • Liver enzyme elevations
  • Bone fractures
  • Allergic reactions including rash or angioedema
  • Seizures (rare)

Precautions & Warnings

Before starting Orgovyx, patients should be evaluated for cardiovascular health and liver function, and ongoing monitoring is recommended throughout therapy.

  • Cardiovascular assessment: review history of heart disease or stroke.
  • Liver function monitoring: perform baseline and periodic liver enzyme tests.
  • Bone health evaluation: consider bone density testing for long‑term use.
  • Drug interactions: review concomitant medications for potential CYP3A4 interactions.
  • Pregnancy and lactation: contraindicated in women; safety not established.
  • Store at ambient temperature: keep below 25 °C, protect from moisture and keep in original packaging.

Avoid Interactions

Orgovyx can interact with several drug classes, requiring careful review of a patient’s medication list.

Major Interactions (Avoid)

  • Strong CYP3A4 inducers (e.g., rifampin, phenytoin): may reduce relugolix exposure.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): may increase relugolix levels.

Moderate Interactions (Monitor Closely)

  • Anticoagulants (e.g., warfarin): may require INR monitoring.
  • Antihypertensives: blood pressure should be observed for additive effects.
  • Hormonal therapies: may alter endocrine balance.
  • Anticonvulsants: monitor for seizure threshold changes.

Frequently Asked Questions

Orgovyx is prescribed for men with advanced prostate cancer or metastatic castration‑sensitive prostate cancer. It works as part of androgen‑deprivation therapy to lower testosterone levels, which helps slow tumor growth and disease progression.

Relugolix is a competitive antagonist of GnRH receptors in the pituitary gland. By blocking these receptors, it suppresses the release of luteinizing hormone and follicle‑stimulating hormone, which in turn reduces testosterone production, a key driver of prostate cancer cell growth.

The prescribed dose of Orgovyx is determined by the treating physician based on the patient’s clinical condition and therapeutic goals. Dosage decisions are individualized and should follow the prescriber’s instructions.

Safety of Orgovyx in pregnancy or while breastfeeding has not been established. The product is contraindicated for use in women, and women of child‑bearing potential should use effective contraception during treatment.

To order Orgovyx, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and import documentation.

Orgovyx is an oral GnRH antagonist, offering rapid testosterone suppression without the initial surge seen with GnRH agonists. Compared with injectable therapies, it avoids injections and can be stopped quickly if needed, providing a convenient alternative for many patients.

Store Orgovyx tablets at ambient temperature, below 25 °C, in the original packaging to protect from moisture. Keep the container tightly closed and out of reach of children.

Orgovyx is taken orally as a tablet, usually with water. Patients should follow the prescribing physician’s instructions regarding timing, food intake and any required concomitant medications.

Serious risks include cardiovascular events such as myocardial infarction, severe hypertension, liver enzyme elevations, bone fractures, and rare allergic reactions. Patients should be monitored regularly for these potential complications.

Orgovyx should not be used by women, individuals with known hypersensitivity to relugolix or any tablet excipients, and patients with uncontrolled cardiovascular disease without appropriate medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Relugolix

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT