Oriduo (Azelastine Hydrochloride, Fluticasone Propionate)

Azelastine hydrochloride is a selective H1‑receptor antagonist. By blocking histamine binding at H1 receptors in the nasal mucosa, it prevents the cascade of events that cause itching, sneezing, and watery discharge, providing rapid symptom relief.

Fluticasone propionate is a potent glucocorticoid. It penetrates nasal cells, binds intracellular glucocorticoid receptors, and suppresses the transcription of inflammatory cytokines, reducing swelling and mucus production for longer‑lasting control of nasal inflammation.

The prescribed dose of Oriduo is determined by a healthcare professional based on the patient’s age, severity of symptoms, and clinical response. Typically, one spray per nostril twice daily is common, but the exact regimen should follow the prescriber’s instructions.

Safety data for Oriduo in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their physician before starting treatment.

To order Oriduo, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Compared with single‑component antihistamine or corticosteroid sprays, Oriduo offers the convenience of a combined therapy, delivering both rapid antihistamine relief and sustained anti‑inflammatory action. This can improve adherence and may provide superior symptom control for patients who need both mechanisms.

Store Oriduo at room temperature, below 25 °C, in its original packaging. Protect the bottle from moisture, excessive heat, and direct sunlight. Keep the spray tip clean and avoid freezing the product.

Oriduo is administered as a nasal spray. The user should gently blow the nose, tilt the head slightly forward, insert the nozzle into each nostril, and press the pump to deliver the prescribed number of sprays. Avoid blowing the nose immediately after dosing.

Serious risks include severe allergic reactions such as anaphylaxis, nasal septum perforation, and rare vision changes or cataract formation with prolonged use. Patients should seek immediate medical attention if they experience difficulty breathing, swelling of the face or throat, persistent nosebleeds, or visual disturbances.