Orkambi Ge (Lumacaftor + Ivacaftor Tablet) 100mg/125mg

ORKAMBI GE combines lumacaftor and ivacaftor in 100mg/125mg tablets to support cystic fibrosis treatment. This fixed-dose therapy is designed for ambient storage and convenient oral use. Suitable for patients indicated by healthcare providers. Always follow professional guidance.

Strength

100mg/125mg

Pack Size

112s

Storage

Ambient

Manufacturer / TM Owner

Vertex Pharmaceuticals

Select Quantity

Pack/s

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Indications & Clinical Uses

ORKAMBI GE (lumacaftor + ivacaftor) is used to treat cystic fibrosis in patients who have specific mutations in the CFTR gene. It helps improve lung function and reduce symptoms by supporting proper protein function. This medication is prescribed for those with two copies of the F508del mutation. It is not a cure but can help manage the condition.

Side Effects

Patients taking ORKAMBI GE may experience improved breathing and fewer respiratory symptoms over time. Some users report better weight maintenance and overall well-being. Common effects include headache, nausea, or mild dizziness, especially when starting treatment. These effects are usually temporary and vary by individual.

Precautions & Warnings

Store ORKAMBI GE at room temperature away from moisture and heat. Keep out of reach of children and pets. Inform your healthcare provider about all medications and supplements you take. Regular medical check-ups are recommended to monitor progress and adjust treatment as needed.

Avoid Interactions

ORKAMBI GE may interact with certain medications, including strong CYP3A inhibitors or inducers. Avoid grapefruit products while taking this drug, as they can alter its effects. Hormonal contraceptives may be less effective, so alternative birth control methods are advised. Always consult a healthcare professional before combining with other therapies.

Frequently Asked Questions

ORKAMBI GE is used to treat cystic fibrosis in patients with specific gene mutations, helping improve lung function and manage symptoms.

Store ORKAMBI GE at room temperature, away from moisture and heat, and keep it out of reach of children.

ORKAMBI GE may interact with certain drugs, so consult a healthcare provider before combining with other therapies.

Common effects include headache, nausea, or mild dizziness, especially when starting treatment.

ORKAMBI GE is not a cure but helps manage symptoms and improve quality of life for eligible patients.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 29 Jul 2026

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