Product image of Orlistat Hexal (Orlistat) supplied by GNH India

Orlistat Hexal

Active Ingredient:
Orlistat
Origin:
EU

Orlistat Hexal (Orlistat)

Orlistat, the active ingredient in Orlistat Hexal, is a lipase inhibitor presented as a unknown/unknown for oral use. It treats obesity and overweight in adults when used with a reduced‑calorie diet and lifestyle changes.

GNH India supplies Orlistat Hexal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Hexal Ag

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Indications & Clinical Uses

Orlistat Hexal is a lipase‑inhibiting anti‑obesity agent that works within the gastrointestinal tract to limit fat absorption.

  • Obesity: helps reduce body weight when combined with diet modification.
  • Overweight: assists in modest weight loss as an adjunct to lifestyle changes.
  • Weight‑related metabolic risk: may improve waist‑circumference and lipid profiles when used as part of a comprehensive weight‑management program.

How It Works

  • Orlistat acts by covalently binding to the active site of gastric and pancreatic lipases in the intestinal lumen. This inhibition prevents the enzymatic breakdown of dietary triglycerides, markedly reducing the absorption of about 30 % of ingested fat, which is then eliminated in the feces.

Side Effects

Orlistat may produce gastrointestinal‑related adverse reactions that are generally mild and reversible.

Common Side Effects

  • Oily spotting of the stool.
  • Increased frequency of bowel movements.
  • Fecal urgency.
  • Flatulence with discharge.
  • Fatty or oily stool.
  • Abdominal cramping.

Serious or Rare Side Effects

  • Oily‑type dermatitis of the perianal area.
  • Severe abdominal pain.
  • Liver enzyme elevations.
  • Acute pancreatitis.
  • Allergic reactions such as urticaria, angio‑edema.
  • Persistent, unexplained gastrointestinal bleeding.

Precautions & Warnings

  • Before ​        ​       ​    ...

Avoid Interactions

  • Major ...

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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