Product image of Orlistato Zentiva (Orlistat) supplied by GNH India

Orlistato Zentiva

Active Ingredient:
Orlistat
Origin:
EU

Orlistato Zentiva (Orlistat)

Orlistat, the active ingredient in Orlistato Zentiva, is a Lip Lip presented as a 120mg tablet for oral use. It inhibits intestinal fat absorption and is indicated for weight management in overweight and obese adults.

GNH India supplies Orlistato Zentiva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.

Manufacturer / TM Owner

Zentiva Portugal, Lda

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Indications & Clinical Uses

Orlistat is used in the management of obesity and related metabolic conditions. It helps:

  • Obesity: Reduces body weight by decreasing dietary fat absorption.
  • Overweight adults with additional risk factors: Supports weight loss when combined with a reduced‑calorie diet.
  • Post‑bariatric surgery patients: Assists in maintaining weight loss after surgical intervention.

How It Works

  • Orlistat acts as a reversible inhibitor of gastric and pancreatic lipases. By binding to the active site of these enzymes, it prevents the hydrolysis of dietary triglycerides into absorbable free fatty acids, thereby reducing the amount of fat that is absorbed from the gastrointestinal tract.

Side Effects

Adverse reactions are generally related to the drug’s mechanism of reducing fat absorption.

Common Side Effects

  • Oily spotting on undergarments.
  • Increased bowel movements.
  • Fecal urgency.
  • Flatulence with discharge.
  • Abdominal cramping.
  • Loose, oily stools.

Serious or Rare Side Effects

  • Severe liver injury.
  • Acute pancreatitis.
  • Allergic reactions such as rash, itching or swelling.
  • Persistent gastrointestinal bleeding.
  • Vitamin D deficiency due to malabsorption.
  • Kidney stones.
  • Unexplained weight loss.
  • Severe abdominal pain.
  • Jaundice.
  • Anaphylaxis.
  • Hepatotoxic 

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Precautions & Warnings

  • Orlistat should be taken 
  • g 
  • t  
  • t \

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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