Product image of Ornique (Ethinylestradiol, Etonogestrel) supplied by GNH India

Ornique

Active Ingredient:
Ethinylestradiol, Etonogestrel
Origin:
EU

Ornique (Ethinylestradiol, Etonogestrel)

Ethinylestradiol, the active ingredient in Ornique, is a combined combinatorial hormonal contraceptive presented as a tablet for oral use. It is used to prevent pregnancy and to regulate menstrual cycles in women of reproductive age.

GNH India supplies Ornique as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Uab Exeltis Baltics

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Indications & Clinical Uses

Ornique, a combined hormonal contraceptive, acts on the reproductive endocrine system to prevent pregnancy and manage menstrual disorders.

  • Contraception: prevention of pregnancy in women of reproductive age.
  • Menstrual cycle regulation: helps achieve regular menstrual bleeding patterns.
  • Acne treatment: reduces acne lesions associated with hormonal fluctuations.

How It Works

  • Ethinylestradiol provides estrogenic activity while etonogestrel supplies progestogenic activity. The estrogen component suppresses follicle‑stimulating hormone, and the progestin component suppresses luteinizing hormone, together inhibiting ovulation. Additionally, progestin thickens cervical mucus and alters the endometrial lining, creating an environment unfavorable for fertilization and implantation.

Side Effects

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Headache: transient tension‑type headaches.
  • Breast tenderness: temporary discomfort in breast tissue.
  • Spotting: irregular vaginal bleeding, especially during the first cycles.

Serious or Rare Side Effects

  • Venous thromboembolism: blood clots in deep veins.
  • Pulmonary embolism: clot migration to lung arteries.
  • Stroke or myocardial infarction: rare cerebrovascular or cardiac events.
  • Severe allergic reaction: anaphylaxis with rash, swelling, or breathing difficulty.

Precautions & Warnings

Before using Ornique, consider the following precautions:

  • Contraindications: known thrombophilia, history of venous thromboembolism, estrogen‑dependent tumor.
  • Smoking: avoid use in women over 35 who smoke more than 15 cigarettes per day.
  • Cardiovascular risk: assess hypertension, diabetes, and hyperlipidaemia.
  • Pregnancy: discontinue immediately if pregnancy is confirmed.
  • Drug interactions: review concomitant medications for potential interactions.
  • Store at ambient temperature: keep in the original pack, protect from moisture and light.

Avoid Interactions

Ornique may interact with several medicines that alter hormone metabolism.

Major Interactions (Avoid)

  • Enzyme‑inducing anticonvulsants (e.g., carbamazepine, phenytoin): may reduce contraceptive efficacy.
  • Rifampin therapy: decreases plasma hormone levels, risking breakthrough bleeding.
  • St. John's wort: herbal inducer that can lower contraceptive effectiveness.

Moderate Interactions (Monitor Closely)

  • Antifungal azoles (e.g., ketoconazole): may increase hormone concentrations, raising side‑effect risk.
  • Macrolide antibiotics (e.g., erythromycin): can elevate plasma levels of etonogestrel.
  • Selective serotonin reuptake inhibitors: may affect bleeding patterns and require monitoring.

Frequently Asked Questions

Ornique is a combined hormonal contraceptive containing ethynylestradiol and etonogestrel. It is prescribed to prevent pregnancy and to help regulate menstrual cycles in women of reproductive age.

Ethynylestradiol provides estrogenic activity while etonogestrel supplies progestogenic activity. Together they suppress the release of gonadotropins, preventing ovulation, thicken cervical mucus, and alter the endometrial lining, creating conditions that inhibit fertilisation and implantation.

The dosing regimen for Ornique is determined by the prescribing healthcare professional. Typically, it is taken as a daily oral tablet, but the exact schedule and duration are individualized based on patient needs and clinical guidelines.

Ornique is contraindicated during pregnancy and should be discontinued if pregnancy occurs. It is generally not recommended for breastfeeding women without medical advice, as hormonal contraceptives may affect milk production and infant exposure.

To order Ornique, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and necessary import documentation.

Ornique contains ethynylestradiol and etonogestrel, a progestin with a favorable safety profile and low androgenic activity. Compared with other combined oral contraceptives, it offers similar contraceptive efficacy while potentially providing better cycle control and a reduced risk of certain hormone‑related side effects.

Ornique tablets should be stored at ambient temperature, below 25 °C, in the original packaging. Protect them from moisture, excessive heat, and direct sunlight to maintain product stability throughout its shelf life.

Ornique is taken orally as a tablet, usually once daily at the same time each day. The tablet is swallowed with water and should not be chewed or broken unless otherwise directed by a healthcare professional.

Serious risks include venous thromboembolism, pulmonary embolism, stroke, myocardial infarction, and severe allergic reactions. Women with a history of clotting disorders, smoking, or cardiovascular disease should discuss these risks with their prescriber before starting Ornique.

Ornique should not be used by women with known thrombophilia, a history of venous thromboembolism, estrogen‑dependent tumors, uncontrolled hypertension, or those who are pregnant. It is also contraindicated in women over 35 who smoke heavily.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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