Product image of Orocal Vitamine D3 (Colecalciferol, Calcium Carbonate) supplied by GNH India

Orocal Vitamine D3

Active Ingredient:
Colecalciferol, Calcium Carbonate
Origin:
EU

Orocal Vitamine D3 (Colecalciferol, Calcium Carbonate)

Colecalciferol, the active ingredient in Orocal Vitamine D3, is a vitamin D supplement presented as an oral supplement for oral use. It helps address vitamin D and calcium deficiencies in adults and children.

GNH India supplies Orocal Vitamine D3 as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Arrow Generiques

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Indications & Clinical Uses

Orocal Vitamine D3 provides vitamin D3 and calcium to support mineral metabolism and bone health. It is indicated for:

  • Vitamin D deficiency: restores adequate serum 25‑hydroxyvitamin D levels.
  • Calcium deficiency: supplies elemental calcium to meet dietary needs.
  • Support of bone health: aids in maintaining normal bone mineralization in at‑risk populations.

How It Works

  • Colecalciferol (vitamin D3) is converted in the liver to 25‑hydroxyvitamin D and subsequently in the kidney to the active hormone 1,25‑dihydroxyvitamin D, which binds to the vitamin D receptor in target tissues. This complex enhances transcription of calcium‑binding proteins, increasing intestinal calcium absorption. Calcium carbonate provides elemental calcium that is absorbed in the gastrointestinal tract, contributing directly to the calcium pool needed for bone mineralization and other physiological functions.

Side Effects

Adverse reactions may occur with oral vitamin D and calcium supplementation.

Common Side Effects

  • Mild gastrointestinal discomfort: nausea, abdominal bloating.
  • Constipation: reduced bowel movements.
  • Hypercalcemia symptoms: fatigue, mild headache.
  • Transient increase in serum calcium: mild thirst.
  • Skin rash: occasional mild erythema.

Serious or Rare Side Effects

  • Severe hypercalcemia: confusion, arrhythmia, renal impairment.
  • Allergic reaction: urticaria, angioedema, anaphylaxis.
  • Hypercalciuria: kidney stone formation.
  • Persistent vomiting or diarrhea leading to dehydration.
  • Unexplained muscle weakness or cramps.

Precautions & Warnings

When using Orocal Vitamine D3, consider the following precautions:

  • Renal impairment: monitor serum calcium and kidney function.
  • Hyperparathyroidism: avoid excess calcium intake.
  • Sarcoidosis or granulomatous disease: risk of hypercalcemia.
  • Concomitant thiazide diuretics: may increase calcium levels.
  • Pregnancy and lactation: use only if prescribed after risk‑benefit assessment.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Orocal Vitamine D3 may interact with several medicines.

Major Interactions (Avoid)

  • Thiazide diuretics: can precipitate hypercalcemia.
  • Vitamin A excess: synergistic risk of hypercalcemia.
  • Digitalis glycosides: increased risk of toxicity with elevated calcium.

Moderate Interactions (Monitor Closely)

  • Anticonvulsants (e.g., phenytoin, phenobarbital): may reduce vitamin D effectiveness.
  • Corticosteroids: can impair calcium absorption.
  • Cholestyramine or other bile‑acid sequestrants: may decrease calcium carbonate absorption.

Frequently Asked Questions

Orocal Vitamine D3 is an oral nutritional supplement that provides vitamin D3 (colecalciferol) and calcium carbonate. It is used to correct vitamin D deficiency, address calcium deficiency, and support normal bone health in individuals who need additional mineral intake.

Colecalciferol is converted in the liver to 25‑hydroxyvitamin D and then in the kidney to the active hormone 1,25‑dihydroxyvitamin D. This active form binds to vitamin D receptors, stimulating the synthesis of calcium‑binding proteins in the intestine, which enhances calcium absorption and promotes bone mineralization.

The appropriate dose of Orocal Vitamine D3 is determined by a qualified healthcare professional based on the patient’s age, baseline vitamin D status, calcium needs, and clinical condition. The prescriber will specify the exact amount and frequency.

Use of Orocal Vitamine D3 during pregnancy or lactation should only be undertaken if prescribed by a healthcare provider. Vitamin D and calcium are essential nutrients, but excessive intake may pose risks, so a professional assessment is required to balance benefits and safety.

To place an order, submit an enquiry on the product page at gnhindia.com, indicating the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Orocal Vitamine D3 combines colecalciferol with calcium carbonate, offering both vitamin D and elemental calcium in a single product. Many alternatives provide only vitamin D3, requiring a separate calcium supplement. The combined formulation can simplify dosing for patients needing both nutrients, but individual needs should be evaluated by a clinician.

Store Orocal Vitamine D3 at ambient temperature, below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Orocal Vitamine D3 is taken orally, usually with water. It can be taken with or without food, but taking it with a meal that contains some fat may improve absorption of the vitamin D component.

The most serious risks involve hypercalcemia, which can cause confusion, cardiac arrhythmias, kidney stones, or renal impairment. Rarely, severe allergic reactions such as anaphylaxis may occur. Patients should seek medical attention if they experience symptoms like persistent vomiting, severe weakness, or unusual heart rhythm.

Individuals with known hypersensitivity to colecalciferol, calcium carbonate, or any excipients should avoid the product. Patients with severe hypercalcemia, uncontrolled hyperparathyroidism, or certain granulomatous diseases should not use it without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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