Product image of Orocalm (Benzydamine Hydrochloride) supplied by GNH India

Orocalm

Active Ingredient:
Benzydamine Hydrochloride
Origin:
EU

Orocalm (Benzydamine Hydrochloride)

Benzydamine Hydrochloride, the active ingredient in Orocalm, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as an oromucosal preparation for local use. It provides anti‑inflammatory, analgesic and antiseptic effects for sore throat, oral mucositis, mouth ulcers and other inflammation of the oral cavity in appropriate patients.

GNH India supplies Orocalm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Melisana Nv

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Indications & Clinical Uses

Benzydamine Hydrochloride acts locally on inflamed oral tissues, relieving pain and reducing inflammation.

  • Sore throat: provides symptomatic relief of pain and swelling in the pharyngeal mucosa.
  • Oral mucositis: reduces inflammation and discomfort associated with chemotherapy or radiotherapy‑induced mucosal injury.
  • Mouth ulcers: promotes analgesia and supports healing of aphthous lesions.
  • Inflammation of the oral cavity: alleviates general irritation and redness of the oral mucosa.

How It Works

  • Benzydamine Hydrochloride exerts its local anti‑inflammatory and analgesic actions by inhibiting prostaglandin synthesis, stabilising cell membranes and reducing the release of inflammatory mediators. The compound also possesses mild antimicrobial activity, contributing to its antiseptic effect on the oral mucosa.

Side Effects

Benzydamine Hydrochloride is generally well tolerated when applied to the oral mucosa, but some adverse reactions may occur.

Common Side Effects

  • Mild burning or stinging sensation at the application site.
  • Transient alteration of taste.
  • Slight oral irritation or redness.
  • Dry mouth sensation.
  • Minor swelling of the lips.

Serious or Rare Side Effects

  • Allergic reactions such as urticaria, angioedema or anaphylaxis.
  • Severe oral mucosal ulceration or necrosis.
  • Contact dermatitis of the perioral skin.

Precautions & Warnings

Before using Orocalm, consider the following safety measures.

  • Pregnancy: consult a healthcare professional before use.
  • Breastfeeding: use with caution and under medical advice.
  • Age: follow prescriber guidance for pediatric or elderly patients.
  • Known hypersensitivity: avoid if allergic to benzydamine or related compounds.
  • Concurrent oral infections: monitor for worsening symptoms.
  • Store at ambient temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Benzydamine Hydrochloride may interact with other agents applied to the oral cavity.

Major Interactions (Avoid)

  • Concurrent use with other topical NSAIDs: may increase local irritation.
  • Alcohol consumption immediately after application: can enhance mucosal burning.

Moderate Interactions (Monitor Closely)

  • Systemic anticoagulants: monitor for increased bleeding if mucosal lesions develop.
  • Chemotherapeutic agents: watch for additive mucosal toxicity.
  • Other oral antiseptics or mouthwashes: risk of cumulative irritation.

Frequently Asked Questions

Orocalm is indicated for the symptomatic relief of sore throat, oral mucositis, mouth ulcers and general inflammation of the oral cavity. It works locally to reduce pain, swelling and microbial irritation in these conditions.

Benzydamine Hydrochloride inhibits prostaglandin synthesis and stabilises cell membranes, which reduces inflammation and pain. It also has mild antimicrobial properties that help control oral micro‑flora, providing a combined anti‑inflammatory, analgesic and antiseptic effect.

The dosage of Orocalm is determined by the prescribing healthcare professional based on the patient’s age, severity of symptoms and clinical judgment. Patients should follow the specific instructions provided on the prescription label or by their clinician.

Safety data for Benzydamine Hydrochloride in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Orocalm.

To request Orocalm, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with systemic NSAIDs, Orocalm provides a targeted local effect, minimizing systemic exposure and related adverse events. Unlike some antiseptic mouthwashes, benzydamine combines anti‑inflammatory, analgesic and antimicrobial actions in a single formulation, offering broader symptom relief for oral inflammation.

Store Orocalm at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed when not in use.

Orocalm is applied directly to the affected oral mucosa. The patient should dispense the recommended amount onto the tongue or affected area, allow it to stay in contact for the prescribed time, and avoid eating or drinking for a short period afterward as advised by the prescriber.

The most serious risks include allergic reactions such as urticaria, angioedema or anaphylaxis, and severe oral ulceration or necrosis. Patients should seek immediate medical attention if they experience swelling of the face, lips, tongue, difficulty breathing, or persistent worsening of oral lesions.

Individuals with a known hypersensitivity to benzydamine hydrochloride or any component of the formulation should avoid using Orocalm. It is also contraindicated in patients who have experienced severe allergic reactions to similar topical NSAIDs, unless directed otherwise by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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