Product image of Orocalm Honing- En Sinaasappelsmaak (Benzydamine Hydrochloride) supplied by GNH India

Orocalm Honing- En Sinaasappelsmaak

Active Ingredient:
Benzydamine Hydrochloride
Origin:
EU

Orocalm Honing- En Sinaasappelsmaak (Benzydamine Hydrochloride)

Benzydamine hydrochloride, the active ingredient in Orocalm Honing- En Sinaasappelsmaak, is a non‑steroidal anti‑inflammatory drug presented as an oral lozenge for topical oral use. It provides symptomatic relief of sore throat and oral mucosal irritation in adults and children.

GNH India supplies Orocalm Honing- En Sinaasappelsmaak as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Melisana Nv

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Indications & Clinical Uses

Benzydamine hydrochloride is used for inflammatory conditions of the oral cavity and pharynx.

  • Sore throat: reduces pain and inflammation in acute pharyngitis.
  • Oral mucositis: alleviates discomfort associated with chemotherapy‑induced mucosal lesions.
  • Post‑operative oral discomfort: provides symptomatic relief after dental or oral surgery.

How It Works

  • Benzydamine hydrochloride exerts its effect by inhibiting the release of pro‑inflammatory cytokines, stabilising mast cells and reducing prostaglandin synthesis, while also possessing local anaesthetic properties that diminish nerve impulse transmission in the oral mucosa. The combined anti‑inflammatory and analgesic actions result in rapid relief of pain and swelling when applied topically.

Side Effects

Benzydamine hydrochloride may cause adverse reactions, most of which are mild and localized.

Common Side Effects

  • Mild burning sensation: transient feeling of warmth at the site of application.
  • Taste alteration: temporary metallic or bitter taste.
  • Mouth dryness: slight reduction in salivation.
  • Nausea: occasional mild nausea.

Serious or Rare Side Effects

  • Allergic reaction: rash, itching, swelling, or difficulty breathing.
  • Severe oral ulceration: persistent ulcerative lesions.
  • Angioedema: rapid swelling of lips or tongue.

Precautions & Warnings

Benzydamine hydrochloride should be used with awareness of specific safety considerations.

  • Pregnancy: safety not established; use only if clearly needed.
  • Breastfeeding: limited data; consider risk versus benefit.
  • Existing oral lesions: avoid if severe ulceration is present.
  • Concomitant anticoagulants: monitor for increased bleeding in oral tissues.
  • Age: use with caution in children under 6 years.
  • Store at ambient temperature: keep in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Benzydamine hydrochloride can interact with other medicines; some interactions require avoidance while others need monitoring.

Major Interactions (Avoid)

  • Anticoagulants: may increase risk of oral bleeding.
  • Other NSAIDs: additive anti‑inflammatory effect may raise gastrointestinal irritation risk.

Moderate Interactions (Monitor Closely)

  • Alcohol: may enhance local irritation.
  • Corticosteroid mouth rinses: monitor for altered healing.
  • Antihistamines: may reduce local anti‑inflammatory effect.

Frequently Asked Questions

Orocalm Honing- En Sinaasappelsmaak is a benzydamine hydrochloride lozenge indicated for the symptomatic relief of sore throat, oral mucositis and post‑operative oral discomfort. It acts locally on inflamed oral and pharyngeal tissues to reduce pain and swelling.

Benzydamine hydrochloride works by inhibiting pro‑inflammatory cytokine release, stabilising mast cells and suppressing prostaglandin synthesis. It also has a local anaesthetic effect that dampens nerve impulse transmission, providing both anti‑inflammatory and analgesic actions when applied to the oral mucosa.

The dosage of Orocalm Honing- En Sinaasappelsmaak is determined by the prescribing healthcare professional based on the patient’s age, severity of symptoms and clinical judgement. No fixed regimen is provided here; the prescriber will specify the appropriate frequency and duration.

Safety data for benzydamine hydrochloride in pregnancy and lactation are limited. It should be used only if the potential benefit justifies the potential risk to the fetus or infant, and the decision should be made by the treating physician in consultation with the patient.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with other topical NSAIDs such as diclofenac mouthwash, benzydamine offers a combined anti‑inflammatory and local anaesthetic effect, leading to rapid pain relief. It is generally well tolerated and does not require systemic absorption, whereas some alternatives may have higher systemic exposure.

Store the lozenges at ambient temperature, below 25 °C, in the original blister pack. Protect them from moisture, direct sunlight and extreme heat. Keep out of reach of children and do not use after the expiry date printed on the packaging.

The product is an oral lozenge. The patient should place one lozenge in the mouth and allow it to dissolve slowly, avoiding chewing. It should not be swallowed whole and should not be taken with other oral medications at the same time to prevent dilution of its local effect.

Serious risks, although rare, include allergic reactions such as rash, itching, swelling or difficulty breathing, as well as severe oral ulceration and angioedema. Any signs of hypersensitivity or persistent ulcerative lesions should prompt immediate medical evaluation.

The lozenge should be avoided in individuals with known hypersensitivity to benzydamine hydrochloride or any excipients, in patients with severe oral ulcerations, and in children younger than six years unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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