Product image of Ortanol (Omeprazole) supplied by GNH India

Ortanol

Active Ingredient:
Omeprazole
Origin:
EU

Ortanol (Omeprazole)

Omeprazole, the active ingredient in Ortanol, is a proton pump inhibitor presented as an oral dosage form for oral use. It reduces gastric acid secretion and is employed in the management of acid‑related gastrointestinal disorders in adults and adolescents.\n\nGNH India supplies Ortanol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Sandoz Gmbh

1
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Indications & Clinical Uses

  • Omeprazole is a proton pump inhibitor used to treat conditions caused by excess gastric acid.\n\nGastro‑esophageal reflux disease (GERD): reduces acid exposure and promotes healing of esophageal irritation.\nPeptic ulcer disease: facilitates ulcer healing by maintaining a higher gastric pH.\nHelicobacter pylori eradication regimens: enhances the effectiveness of antibiotic combinations.\nErosive esophagitis: promotes mucosal recovery by suppressing acid secretion.

How It Works

  • Omeprazole irreversibly binds to the H+/K+ ATPase enzyme (gastric proton pump) located on the secretory surface of parietal cells. By inhibiting this final step of acid production, it markedly lowers both basal and stimulated gastric acid output, creating a less acidic gastric environment that supports healing of acid‑related lesions.

Side Effects

  • Adverse reactions may occur with any dose of omeprazole.\n\nCommon Side Effects:\n- Headache: mild to moderate intensity.\n- Diarrhea: usually transient.\n- Nausea or vomiting: occasional gastrointestinal upset.\n- Abdominal pain: cramp‑like discomfort.\n- Flatulence: increased gas production.\n- Constipation: reduced bowel movements.\n\nSerious or Rare Side Effects:\n- Severe allergic reactions: rash, swelling, or anaphylaxis.\n- Clostridioides difficile infection: persistent diarrhea with possible colitis.\n- Low magnesium levels: muscle cramps, seizures, or cardiac arrhythmia.\n- Bone fractures: increased risk with long‑term use.\n- Liver enzyme elevation: hepatitis or jaundice.

Precautions & Warnings

  • Before initiating therapy, consider the following precautions.\n\nAssess renal and hepatic function: dose adjustment may be required in severe impairment.\nMonitor for infection: prolonged acid suppression can predispose to gastrointestinal infections.\nEvaluate need for long‑term use: reassess benefits versus risks periodically.\nAvoid abrupt discontinuation: may cause rebound acid hypersecretion.\nStore at ambient temperature: keep below 25°C in the original container, protect from moisture and direct sunlight.

Avoid Interactions

  • Omeprazole may alter the pharmacokinetics of several co‑administered drugs.\n\nMajor Interactions (Avoid):\n- Clopidogrel: reduced antiplatelet effect, increasing cardiovascular risk.\n- Atazanavir or other protease inhibitors: markedly decreased absorption, compromising antiviral efficacy.\n\nModerate Interactions (Monitor Closely):\n- Warfarin: potential increase in INR, monitor coagulation parameters.\n- Methotrexate (high dose): possible accumulation, watch for toxicity.\n- Digoxin: modest increase in serum levels, consider dose adjustment.

Frequently Asked Questions

Ortalon contains omeprazole, a proton pump inhibitor that is used to lower stomach acid. It is indicated for conditions such as gastro‑esophageal reflux disease, peptic ulcer disease, Helicobacter pylori eradication regimens, and erosive esophagitis, helping to relieve symptoms and promote healing of the gastrointestinal lining.

Omeprazole acts by irreversibly inhibiting the H+/K+ ATPase enzyme, also known as the gastric proton pump, on the surface of parietal cells. This blockade stops the final step of acid production, resulting in a sustained reduction of gastric acidity and allowing damaged tissues to recover.

The appropriate dose of Ortanol is determined by the prescribing healthcare professional based on the specific condition, severity, and patient characteristics. Dosage recommendations are individualized and should follow the prescriber’s instructions and local prescribing guidelines.

Safety data for omeprazole in pregnancy and lactation are limited. The drug should only be used if the potential benefit justifies any possible risk to the fetus or infant. Healthcare providers will assess the risk‑benefit profile before prescribing to pregnant or nursing women.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ortalon (omeprazole) belongs to the proton pump inhibitor class, which provides more potent and longer‑lasting acid suppression than H2‑receptor antagonists such as ranitidine. Compared with newer PPIs, omeprazole has a well‑established efficacy and safety profile, making it a common first‑line choice for acid‑related disorders.

Ortalon should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Ortalon is taken orally, usually as a whole tablet or capsule, with a glass of water. It can be taken with or without food, but consistent timing each day helps maintain steady acid suppression. Patients should follow the prescriber’s directions regarding timing relative to meals.

Serious adverse events, though rare, include severe allergic reactions (anaphylaxis), Clostridioides difficile‑associated diarrhea, low magnesium levels leading to muscle cramps or cardiac arrhythmias, and an increased risk of bone fractures with long‑term use. Any concerning symptoms should be reported to a healthcare professional promptly.

Ortalon is contraindicated in individuals with known hypersensitivity to omeprazole or any component of the formulation. Patients with severe liver disease should use it with caution, and those taking medications that rely on gastric acidity for absorption (e.g., certain antifungals or antivirals) should discuss alternatives with their prescriber.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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