Orudis (Ketoprofen)

Ketoprofen works by inhibiting the cyclo‑oxygenase enzymes COX‑1 and COX‑2, which are needed for the production of prostaglandins. Lower prostaglandin levels reduce inflammation, pain signalling and fever, providing symptomatic relief in affected tissues.

The appropriate dose of Orudis is determined by the prescribing clinician based on the patient’s condition, severity of symptoms, age, renal and hepatic function, and any concomitant medications. The prescriber will set the exact dosage and schedule.

Ketoprofen is generally avoided in the third trimester of pregnancy because it may affect fetal ductus arteriosus closure. Use during earlier stages or while breastfeeding should only be considered if the potential benefit outweighs the risk and after consultation with a healthcare professional.

To order Orudis, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ketoprofen offers analgesic and anti‑inflammatory potency comparable to ibuprofen and diclofenac, with a relatively rapid onset of action. Its COX‑inhibition profile is similar to other non‑selective NSAIDs, but individual patient response and tolerability may differ, influencing drug choice.

Store Orudis tablets at temperatures below 25 °C in the original container, protecting them from moisture and light. Keep the product out of reach of children and do not use if the packaging is damaged.

Orudis is administered orally as a tablet. It should be swallowed whole with water, preferably with food or a glass of milk to minimise gastrointestinal irritation.

Serious risks include gastrointestinal ulceration or bleeding, renal impairment, hepatotoxicity, severe skin reactions such as Stevens‑Johnson syndrome, and anaphylaxis. Patients should be monitored for signs of these events and seek immediate medical attention if they occur.

Orudis should be avoided by individuals with known hypersensitivity to ketoprofen or other NSAIDs, those with active gastrointestinal ulceration, severe heart failure, advanced renal or hepatic disease, and pregnant women in the third trimester. Consultation with a healthcare professional is essential before starting therapy.