Product image of Osmille D (Colecalciferol, Calcium Carbonate) supplied by GNH India

Osmille D

Active Ingredient:
Colecalciferol, Calcium Carbonate
Origin:
EU

Osmille D (Colecalciferol, Calcium Carbonate)

Colecalciferol, the active ingredient in Osmille D, is a vitamin D supplement presented as an oral dosage form for oral use. Together with calcium carbonate, it supports calcium absorption and is indicated for individuals with calcium or vitamin D deficiency and for the prevention of bone demineralisation.

GNH India supplies Osmille D as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory support for global distribution.

Manufacturer / TM Owner

Italfarmaco S.A.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Osmille D is used to address deficiencies in calcium and vitamin D, which are essential for bone health.

  • Calcium deficiency: helps restore normal calcium levels and supports bone mineralisation.
  • Vitamin D deficiency: increases serum 25‑hydroxyvitamin D concentrations, improving calcium absorption.
  • Osteoporosis prevention: provides essential nutrients to reduce bone loss in at‑risk populations.

How It Works

  • Colecalciferol (vitamin D3) is metabolised in the liver to 25‑hydroxyvitamin D and then to the active hormone 1,25‑dihydroxyvitamin D, which binds to the vitamin D receptor in intestinal cells, up‑regulating calcium‑transport proteins and enhancing calcium uptake. Calcium carbonate dissociates in the acidic stomach environment to release elemental calcium, supplying the mineral required for bone matrix formation.

Side Effects

Oral administration of Osmille D may be associated with a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Nausea: mild stomach upset after ingestion.
  • Constipation: reduced bowel movements.
  • Abdominal discomfort: cramps or bloating.
  • Hypercalcemia symptoms: mild fatigue or thirst.

Serious or Rare Side Effects

  • Hypercalcemia: severe elevated calcium levels causing confusion or cardiac arrhythmia.
  • Kidney stones: formation due to excess calcium.
  • Allergic reaction: rash, itching, swelling, or difficulty breathing.
  • Hypervitaminosis D: toxicity presenting with vomiting, weakness, or renal impairment.

Precautions & Warnings

Before using Osmille D, consider the following precautions to ensure safe and effective therapy.

  • Assess calcium status: evaluate serum calcium levels in patients with known disorders.
  • Monitor renal function: patients with kidney disease may accumulate calcium.
  • Review medication list: avoid concurrent high‑dose calcium or vitamin D supplements without supervision.
  • Pregnancy and lactation: use only if prescribed after risk‑benefit assessment.
  • Store at ambient temperature: keep below 25 °C in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Osmille D can interact with certain medicines, altering calcium or vitamin D metabolism.

Major Interactions (Avoid)

  • Thiazide diuretics: may increase risk of hypercalcemia.
  • Vitamin D analogues (e.g., calcitriol): can cause excessive calcium levels.
  • Calcium‑containing antacids: may lead to calcium overload.

Moderate Interactions (Monitor Closely)

  • Corticosteroids: may reduce calcium absorption, requiring monitoring.
  • Anticonvulsants (e.g., phenytoin, phenobarbital): can accelerate vitamin D metabolism.
  • Bisphosphonates: concurrent use may affect bone turnover dynamics.

Frequently Asked Questions

Osmille D is a nutritional supplement that provides vitamin D3 (colecalciferol) and calcium carbonate. It is used to correct calcium and vitamin D deficiencies, support normal bone mineralisation, and help prevent osteoporosis in individuals at risk of bone loss.

Colecalciferol is converted in the liver to 25‑hydroxyvitamin D and then to the active hormone 1,25‑dihydroxyvitamin D. This hormone binds to vitamin D receptors in the intestine, stimulating the synthesis of calcium‑binding proteins and increasing the efficiency of dietary calcium absorption.

The appropriate dose of Osmille D is determined by the prescribing healthcare professional based on the patient’s age, baseline calcium and vitamin D status, underlying medical conditions, and any concurrent medications. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Osmille D may be used during pregnancy or lactation only if the prescriber judges that the potential benefits outweigh any possible risks. Vitamin D and calcium are important for fetal bone development, but dosing should be individualized and supervised by a healthcare provider.

To order Osmille D, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Osmille D combines colecalciferol and calcium carbonate in a single oral formulation, offering both vitamin D3 and a readily absorbable source of elemental calcium. Compared with products that contain only calcium or only vitamin D, Osmille D provides a convenient dual‑nutrient approach, which can simplify dosing and improve adherence when both nutrients are needed.

Store Osmille D at ambient temperature, preferably below 25 °C. Keep the tablets in the original packaging, protect them from moisture, excessive heat and direct sunlight. Do not store in the refrigerator or freezer, as this may affect tablet integrity.

Osmille D is taken orally, usually with a glass of water. It can be swallowed with or without food, unless the prescribing clinician advises otherwise. Patients should follow the dosage schedule provided by their healthcare professional.

The most serious risks include hypercalcemia, which can cause confusion, cardiac arrhythmias, or kidney stones, and rare cases of severe allergic reactions such as anaphylaxis. Prompt medical attention is required if symptoms of high calcium levels or allergic responses develop.

Individuals with known hypersensitivity to colecalciferol, calcium carbonate, or any excipients in the product should avoid Osmille D. Patients with hypercalcemia, severe renal impairment, or certain granulomatous diseases should not use it unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.