Product image of Otrivin Allergy (Dimetindene Maleate, Phenylephrine) supplied by GNH India

Otrivin Allergy

Active Ingredient:
Dimetindene Maleate, Phenylephrine
Origin:
EU

Otrivin Allergy (Dimetindene Maleate, Phenylephrine)

Dimetindene maleate and phenylephrine, the active ingredients in Otrivin Allergy, are an antihistamine and a nasal decongestant presented as a nasal spray for intranasal use. They alleviate allergic rhinitis by reducing nasal congestion, itching, and sneezing in adults and children experiencing seasonal or perennial allergy symptoms.

GNH India supplies Otrivin Allergy as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company ensures quality and regulatory compliance across EU and global markets with reliable logistics and product traceability.

Manufacturer / TM Owner

Haleon Poland Sp. Z O.O.

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Indications & Clinical Uses

  • Otrivin Allergy combines an antihistamine and a decongestant to treat allergic rhinitis and related nasal symptoms.
  • Allergic rhinitis: relief of nasal itching, sneezing, and congestion.
  • Nasal congestion due to allergies: reduction of swelling in the nasal passages.
  • Seasonal allergic rhinitis: control of symptoms during pollen season.

How It Works

  • Dimetindene maleate acts as an H1‑receptor antagonist, blocking histamine binding and preventing the cascade that leads to itching, swelling, and increased secretions. Phenylephrine is an α1‑adrenergic agonist that causes vasoconstriction of nasal mucosal vessels, decreasing blood flow and reducing congestion, thereby providing combined antihistamine and decongestant effects.

Side Effects

Common Side Effects

  • Nasal irritation or burning sensation.
  • Dryness of the nasal mucosa.
  • Mild headache.
  • Transient taste disturbance.

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis).
  • Significant increase in blood pressure or hypertension.
  • Cardiac arrhythmias.
  • Nasal ulceration or severe epistaxis.
  • Paradoxical worsening of nasal congestion.

Precautions & Warnings

Before using Otrivin Allergy, consider the following precautions:

  • Assess for hypersensitivity: avoid use if known allergy to dimetindene, phenylephrine or other components.
  • Use with caution in hypertension: phenylephrine may raise blood pressure.
  • Avoid prolonged use: limit to recommended duration to prevent rebound congestion.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Drug interactions: review concomitant MAO inhibitors or other vasoconstrictors.
  • Store at room temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Otrivin Allergy may interact with other medicines as follows:

Major Interactions (Avoid)

  • MAO inhibitors: risk of hypertensive crisis.
  • Other nasal decongestants: additive vasoconstriction.
  • Beta‑blockers: may reduce antihistamine efficacy.

Moderate Interactions (Monitor Closely)

  • Antihypertensive agents: monitor blood pressure.
  • Anticholinergic drugs: possible additive dryness.
  • Alcohol: may increase drowsiness from the antihistamine component.

Frequently Asked Questions

Otrivin Allergy is an over‑the‑counter nasal spray that combines dimetindene maleate, an antihistamine, with phenylephrine, a decongestant. It is intended to relieve symptoms of allergic rhinitis such as nasal congestion, itching, sneezing and a runny nose caused by seasonal or perennial allergies.

Dimetindene maleate blocks H1 histamine receptors in the nasal mucosa, preventing histamine from binding and triggering the cascade that leads to itching, swelling, and increased secretions. By antagonizing these receptors, it reduces the allergic response and associated nasal symptoms.

The exact dose and frequency are determined by the prescribing healthcare professional based on the patient’s age, severity of symptoms and local labeling. Typically, the product is administered as a few sprays into each nostril, but the prescriber sets the specific regimen.

Safety data for dimetindene maleate and phenylephrine during pregnancy and lactation are limited. Women who are pregnant, planning pregnancy, or breastfeeding should consult their physician before using Otrivin Allergy to weigh potential benefits against any possible risks.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with single‑ingredient antihistamine sprays, Otrivin Allergy adds phenylephrine, providing both antihistamine relief and immediate decongestion. This dual action can be more effective for patients with prominent nasal blockage, whereas pure antihistamine sprays mainly address itching and sneezing.

Otrivin Allergy should be stored at room temperature, below 25 °C, in its original container. Keep the bottle tightly closed, protect it from moisture and direct sunlight, and keep it out of reach of children.

The spray is used intranasally. After gently shaking the bottle, the user inserts the tip into one nostril, closes the opposite nostril, and presses the actuator to deliver the recommended number of sprays. The process is then repeated in the other nostril if directed by the prescriber.

Although uncommon, serious adverse reactions can include severe allergic responses such as anaphylaxis, significant hypertension, arrhythmias, or nasal ulceration. Any signs of difficulty breathing, rapid heartbeat, severe nosebleeds, or swelling of the face or throat require immediate medical attention.

Individuals with known hypersensitivity to dimetindene, phenylephrine or any excipients in the formulation should avoid the product. It is also contraindicated in patients taking monoamine oxidase inhibitors, other nasal decongestants, or those with uncontrolled high blood pressure unless advised by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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