Product image of Otrivin Extra (Xylometazoline Hydrochloride, Dexpanthenol) supplied by GNH India

Otrivin Extra

Active Ingredient:
Xylometazoline Hydrochloride, Dexpanthenol
Origin:
EU

Otrivin Extra (Xylometazoline Hydrochloride, Dexpanthenol)

Xylometazoline hydrochloride, the active ingredient in Otrivin Extra, is an alpha‑adrenergic agonist presented as a nasal spray for topical intranasal use. It relieves nasal congestion in adults and children. GNH India supplies Otrivin Extra as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.

GNH India supplies Otrivin Extra as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.

Manufacturer / TM Owner

Haleon Hungary Kft.

1
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Indications & Clinical Uses

Otrivin Extra contains Xylometazoline, an alpha‑adrenergic vasoconstrictor that reduces swelling of nasal mucosa.

  • Common cold: alleviates nasal congestion and improves airflow.
  • Allergic rhinitis: decreases nasal blockage caused by seasonal allergens.
  • Sinusitis: helps relieve congestion associated with acute sinus inflammation.

How It Works

  • Xylometazoline hydrochloride acts as a selective alpha‑2 adrenergic receptor agonist on the vascular smooth muscle of the nasal mucosa, causing vasoconstriction. This reduces blood flow to the swollen tissues, decreasing edema and opening the nasal passages. Dexpanthenol provides a moisturizing effect that supports mucosal integrity.

Side Effects

Adverse reactions to Otrivin Extra are generally mild and transient.

Common Side Effects

  • Nasal burning or stinging sensation.
  • Mild nasal dryness.
  • Sneezing.
  • Headache.
  • Transient taste disturbance.

Serious or Rare Side Effects

  • Persistent nasal irritation or ulceration.
  • Severe hypertension.
  • Allergic reaction such as rash, itching, or swelling.
  • Nasal bleeding (epistaxis) that does not stop.
  • Rebound congestion with prolonged use.

Precautions & Warnings

When using Otrivin Extra, consider the following safety measures:

  • Age restriction: not for children under 6 years without medical advice.
  • Duration limit: limit use to 3‑5 days to avoid rebound congestion.
  • Pre‑existing conditions: use cautiously in patients with hypertension, heart disease, diabetes, or thyroid disorders.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Drug interactions: review concomitant nasal or systemic decongestants.
  • Store at ambient temperature: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Xylometazoline may interact with other medications that affect blood pressure or vascular tone.

Major Interactions (Avoid)

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Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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