Otrivine Menthol Abschwellend (Xylometazoline Hydrochloride)

Xylometazoline hydrochloride, the active ingredient in Otrivine Menthol Abschwellend, is a decongestant presented as a nasal spray for topical intranasal use. It relieves nasal congestion associated with colds, sinusitis and allergic rhinitis in adults and children. GNH India supplies Otrivine Menthol Abschwellend as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

GNH India supplies Otrivine Menthol Abschwellend as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Haleon Belgium

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Indications & Clinical Uses

Otrivine Menthol Abschwellend contains a nasal decongestant that acts on the upper‑respiratory tract to reduce swelling of the nasal mucosa.

Common cold: alleviates nasal blockage and improves airflow.
Acute sinusitis: decreases mucosal edema, facilitating sinus drainage.
Allergic rhinitis: reduces nasal congestion caused by seasonal allergens.
Nasal surgery recovery: helps maintain clear airways post‑operatively.

How It Works

Xylometazoline hydrochloride is an alpha‑2‑adrenergic agonist that binds to receptors on the smooth muscle of nasal blood vessels. Activation causes vasoconstriction, which reduces blood flow to the nasal mucosa, decreasing swelling and opening the nasal passages for easier breathing.

Side Effects

Side effects are generally mild and related to local irritation of the nasal mucosa.

Common Side Effects

Nasal burning or stinging sensation.
Mild headache.
Dryness or crusting inside the nose.
Sneezing shortly after application.
Transient taste disturbance.

Serious or Rare Side Effects

Persistent nasal irritation or ulceration.
Severe headache or facial pain.
Hypertension or increased heart rate.
Allergic reaction such as rash, itching or swelling.
Rebound congestion with prolonged use beyond recommended duration.

Precautions & Warnings

Before using Otrivine Menthol Abschwellend, consider the following safety measures:

Contraindication: Do not use if known allergy to xylometazoline or menthol.
Age restriction: Avoid use in children under 6 years unless directed by a physician.
Duration limit: Limit use to no more than 5‑7 consecutive days to prevent rebound congestion.
Pre‑existing conditions: Use with caution in patients with hypertension, heart disease, diabetes.
Interactions: Avoid concurrent use with other nasal decongestant sprays.
Store at room temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Xylometazoline may interact with other medications that affect vascular tone or blood pressure.

Major Interactions (Avoid)

Monoamine oxidase inhibitors (MAOIs): increased risk of hypertensive crisis.
Other topical nasal decongestants: risk of additive vasoconstriction and rebound congestion.

Moderate Interactions (Monitor Closely)

Systemic decongestants (e.g., pseudo‑pseudohypoxia.
Antihypertensive drugs: possible attenuation of blood‑pressure‑lowering effect.
Beta‑blockers.
Tricyclic antidepressants.