Product image of Ottoflox (Ofloxacin) supplied by GNH India

Ottoflox

Active Ingredient:
Ofloxacin
Origin:
EU

Ottoflox (Ofloxacin)

Ofloxacin, the active ingredient in Ottoflox, is a fluoroquinolone antibiotic presented as a tablet for oral use. It treats bacterial infections in adults and children when prescribed by a healthcare professional.

GNH India supplies Ottoflox as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratório Edol - Produtos Farmacêuticos, S.A.

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Indications & Clinical Uses

Ottoflox is a fluoroquinolone antibiotic that targets bacterial DNA replication pathways. It is commonly used for:

  • Urinary tract infection: helps clear the infection and relieve symptoms.
  • Respiratory tract infection: aids in the eradication of pathogenic bacteria causing bronchitis and pneumonia.
  • Skin and soft‑tissue infection: assists in reducing bacterial load and promoting healing.

How It Works

  • Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA supercoiling and replication. By blocking these enzymes, the drug prevents bacterial cells from duplicating their genetic material, leading to bactericidal activity against a broad spectrum of Gram‑negative and some Gram‑positive organisms.

Side Effects

Adverse reactions to Ofloxacin may vary in frequency and severity.

Common Side Effects

  • Nausea
  • Diarrhea
  • Headache
  • Dizziness
  • Abdominal pain

Serious or Rare Side Effects

  • Tendon rupture or inflammation
  • Peripheral neuropathy
  • Severe skin reactions such as Stevens‑Johnson syndrome
  • QT interval prolongation
  • Clostridioides difficile‑associated colitis

Precautions & Warnings

When using Ofloxacin, several safety considerations should be observed:

  • Renal impairment: dose adjustment may be required.
  • Hepatic impairment: monitor liver function tests.
  • Concomitant use with antacids or supplements containing magnesium or aluminum: may reduce absorption.
  • History of tendon disorders: avoid prolonged therapy.
  • Pregnancy and lactation: use only if clearly needed.

Store at below 25°C: keep in the original packaging, protect from moisture and light.

Avoid Interactions

Ofloxacin can interact with several other medicines, affecting its efficacy or safety profile.

Major Interactions (Avoid)

  • Warfarin : Increased risk of bleeding due to enhanced anticoagulant effect.
  • Theophylline : Elevated theophylline levels and risk of toxicity.
  • Cyclosporine : Higher risk of nephrotoxicity and nephritis ‑ monitor renal function.

Moderate Interactions (Monitor Closely):

  • Antacids containing magnesium/aluminum : Reduced absorption of Ofloxacin.
  • Non‑steroidal anti‑inflammatory NSAIDs : Potential for increased CNS side‑effects.
  • Diabetic medications : Possible alteration of glucose control, requiring monitoring.

Frequently Asked Questions

Ottoflox contains Ofloxacin, a fluoroquinolone antibiotic that is prescribed to treat a range of bacterial infections such as urinary tract infections, respiratory tract infections, and skin‑and‑soft‑tissue infections when a healthcare professional determines it is appropriate.

Ofloxacin works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes that are essential for DNA replication and transcription. This inhibition stops bacterial cells from multiplying, leading to a bactericidal effect against susceptible organisms.

The dosage of Ottoflox is set by the prescribing clinician based on the type and severity of the infection, patient age, weight, kidney function and other clinical factors. Patients should follow the prescriber’s instructions and the product label.

Ofloxacin is classified as pregnancy‑category C in many regions, meaning it should only be used when the potential benefit justifies the potential risk to the fetus. It is excreted in breast milk, so breastfeeding mothers should use it only if clearly needed and after consulting a healthcare professional.

To order Ottoflox, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Ottoflox (Ofloxacin) shares the class‑wide mechanism of DNA‑gyrase inhibition with other fluoroquinolones such as ciprofloxacin and levofloxacin. Compared with some alternatives, Ofloxacin offers a broad spectrum against Gram‑negative organisms and good oral bioavailability, but individual drug choice depends on local resistance patterns and patient‑specific factors.

Ottoflox tablets should be stored at temperatures below 25 °C, in the original container, protected from moisture and direct light. This helps maintain potency throughout the product’s shelf‑life.

Ottoflox is supplied as oral tablets that are taken with a full glass of water. It may be taken with or without food, but patients should avoid concurrent intake of antacids or mineral supplements that could interfere with absorption.

Serious adverse reactions to Ofloxacin include tendon rupture or inflammation, peripheral neuropathy, severe skin reactions such as Stevens‑Johnson syndrome, QT‑interval prolongation and Clostridioides difficile‑associated colitis. Patients should seek immediate medical attention if they experience any of these events.

Ottoflox should be avoided in individuals with a known hypersensitivity to fluoroquinolones, those with a history of tendon disorders related to fluoroquinolone use, and patients taking medications that have major interactions unless closely monitored. It is also contraindicated in pregnancy unless clearly indicated.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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