Product image of Oxaliplatin Hikma (Oxaliplatin) supplied by GNH India

Oxaliplatin Hikma

Active Ingredient:
Oxaliplatin
Origin:
EU

Oxaliplatin Hikma (Oxaliplatin)

Oxaliplatin, the active ingredient in Oxaliplatin Hikma, is a platinum‑based chemotherapy presented as a sterile powder for intravenous infusion use. It treats colorectal cancer and other solid tumours in adult patients.
GNH India supplies Oxaliplatin Hikma as a licensed, GDP‑compliant international pharmaceutical supplier serving oncology centres, hospitals and pharmacies worldwide.

Manufacturer / TM Owner

Hikma Farmacêutica (Portugal), S.A.

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Indications & Clinical Uses

Oxaliplatin Hikma is used in the treatment of cancers that are part of the colorectal and gastrointestinal tumour pathway.

  • Colorectal cancer: improves survival by inhibiting tumor cell replication.
  • Gastric cancer: used in combination regimens to reduce tumor burden.
  • Pancreatic cancer: contributes to disease control when combined with other agents.

How It Works

  • Oxaliplatin exerts its anticancer activity by forming platinum‑DNA adducts that cause intra‑strand cross‑links, disrupting DNA replication and transcription. This triggers cell‑cycle arrest and apoptosis in rapidly dividing tumor cells.

Side Effects

Oxaliplatin may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Nausea and vomiting: frequent gastrointestinal upset.
  • Peripheral neuropathy: tingling or numbness in the hands and feet.
  • Fatigue: persistent tiredness not relieved by rest.
  • Diarrhoea: loose stools that may require hydration.
  • Thrombocytopenia: reduced platelet count increasing bleed risk.

Serious or Rare Side Effects

  • Severe allergic reactions: anaphylaxis or bronchospasm.
  • Acute neurotoxicity: sudden onset of muscle cramps or difficulty breathing.
  • Hemolytic‑uremic syndrome: rare kidney injury with low platelets.
  • Cardiac arrhythmias: irregular heart rhythms observed during infusion.

Precautions & Warnings

When using Oxaliplatin Hikma, careful monitoring and patient assessment are essential.

  • Renal function: assess  
  • Cardiac  

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Avoid Interactions

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Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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