Oxazepam Auro (Oxazepam)

Oxazepam is a benzodiazepine that acts on the central nervous system to relieve anxiety‑related conditions.

• Generalized Anxiety Disorder: reduces excessive worry and tension.
• Acute Alcohol Withdrawal: alleviates agitation, tremor and risk of seizures.
• Pre‑operative Sedation: provides calming effect before surgical procedures.
• Muscle Spasm Relief: helps relax skeletal muscle tone associated with anxiety‑induced tension.
• Insomnia Related to Anxiety: improves sleep onset when anxiety is a contributing factor.

• Oxazepam binds selectively to the gamma‑aminobutyric acid‑A (GABA‑A) receptor complex, enhancing the inhibitory action of GABA. This potentiation increases chloride ion influx, hyper‑polarising neuronal membranes and reducing neuronal excitability, which produces anxiolytic, sedative and muscle‑relaxant effects.

Oxazepam may cause a range of adverse reactions, from mild to potentially serious.

Common Side Effects

• Drowsiness
• Dizziness
• Headache
• Fatigue
• Nausea
• Impaired coordination

Serious or Rare Side Effects

• Respiratory depression
• Severe hypotension
• Paradoxical aggression or agitation
• Hepatic dysfunction
• Skin reactions such as Stevens‑Johnson syndrome
• Dependence or withdrawal syndrome upon abrupt discontinuation

When prescribing Oxazepam, clinicians should consider several safety aspects.

• Pregnancy: avoid use unless clearly needed, as risks to the fetus are not fully known.
• Breastfeeding: contraind 
• Elderly Patients: start with lower doses and monitor for excessive sedation.
• Concomitant CNS Depressants: increase risk of profound sedation and respiratory depression.
• History of Substance Abuse: assess risk of dependence before initiating therapy.
• Store at ambient: keep the tablets in the original packaging 
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