Product image of Oxiconazole Nitrate (Oxiconazole Nitrate) 10 mg/g Cream supplied by GNH India

Oxiconazole Nitrate (Oxiconazole Nitrate)

Active Ingredient:
Oxiconazole Nitrate (Oxiconazole Nitrate)
Form:
Cream
Brand:
Oxiconazole Nitrate
Origin:
US

Oxiconazole Nitrate (Oxiconazole Nitrate) (Cream) 10 mg/g

Oxiconazole nitrate, the active ingredient in Oxiconazole Nitrate, is an imidazole antifungal presented as a 10 mg/g cream for topical use. It is used to treat fungal skin infections such as tinea corporis, tinea cruris, tinea pedis, and candidal skin infections. GNH India supplies Oxiconazole Nitrate as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

GNH India is a trusted supplier of high-quality pharmaceuticals, ensuring that Oxiconazole Nitrate meets international standards for safety and efficacy.

Strength

10 mg/g

Manufacturer / TM Owner

Taro Pharmaceuticals U.S.A., Inc.

1
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Indications & Clinical Uses

Oxiconazole Nitrate is an antifungal medication used to treat various fungal skin infections. It is effective against a range of dermatophytes and yeasts. Common uses include:

  • Tinea corporis: Treats ringworm infections on the body.
  • Tinea cruris: Treats jock itch, a fungal infection in the groin area.
  • Tinea pedis: Treats athlete's foot, a fungal infection of the feet.
  • Candidal skin infections: Treats skin infections caused by Candida species.

How It Works

  • Oxiconazole nitrate works by inhibiting the synthesis of ergosterol, a crucial component of fungal cell membranes. It blocks the fungal cytochrome P450 enzyme lanosterol 14α-demethylase, leading to disruptions in cell membrane integrity and fungal cell death. This mechanism makes it effective against a wide range of pathogenic fungi.

Side Effects

Oxiconazole Nitrate may cause side effects, although not everyone experiences them. Common Side Effects:

  • Skin irritation
  • Itching
  • Burning sensation
  • Redness
  • Dryness

Serious or Rare Side Effects

  • Severe skin irritation
  • Allergic reactions
  • Hyperpigmentation
  • Increased irritation at the application site

Precautions & Warnings

Oxiconazole Nitrate should be used with caution to ensure safety and effectiveness. Important precautions include:

  • Avoid contact with eyes and mucous membranes: Rinse immediately if contact occurs.
  • Discontinue use if irritation occurs: Notify your physician if the area becomes more irritated.
  • Inform your physician of any worsening symptoms: Notify the physician if there is no improvement after 2 to 4 weeks.
  • Use as directed: Follow the prescribed dosage and application instructions.
  • Store below 25°C: Keep in the original pack, protect from moisture.

Avoid Interactions

Oxiconazole Nitrate may interact with other medications, so it is important to discuss all current treatments with your physician. Major Interactions (Avoid):

  • None identified.

Moderate Interactions (Monitor Closely)

  • Other topical antifungal agents: May increase the risk of skin irritation.
  • Topical corticosteroids: May enhance the effects of oxiconazole nitrate, requiring careful monitoring.

Frequently Asked Questions

Oxiconazole Nitrate is used to treat various fungal skin infections, including tinea corporis (ringworm), tinea cruris (jock itch), tinea pedis (athlete's foot), and candidal skin infections. It is applied topically to the affected areas to combat fungal growth and alleviate symptoms.

Oxiconazole Nitrate works by inhibiting the synthesis of ergosterol, a key component of fungal cell membranes. By blocking the enzyme lanosterol 14α-demethylase, it disrupts the cell membrane integrity of fungi, leading to their death. This mechanism makes it effective against a wide range of pathogenic fungi.

The usual dose of Oxiconazole Nitrate is determined by your physician based on the type and severity of the infection. It is typically applied once or twice daily to the affected area. Always follow the prescribed dosage and application instructions provided by your healthcare provider.

The safety of Oxiconazole Nitrate during pregnancy or breastfeeding has not been established. It is important to consult with your physician before using this medication if you are pregnant, planning to become pregnant, or breastfeeding. Your healthcare provider can provide guidance based on your specific situation.

To order Oxiconazole Nitrate from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets. The team will ask you to confirm your trade or institutional credentials and will reply with pricing, availability, shipping, and the necessary import paperwork.

Oxiconazole Nitrate is an effective antifungal medication that works by inhibiting ergosterol synthesis in fungal cells. Compared to other antifungal treatments, it is specifically formulated to treat dermatophyte and yeast infections. Your physician can recommend the most suitable treatment based on the type of infection and your medical history.

Oxiconazole Nitrate should be stored below 25°C, keeping it in the original pack and protecting it from moisture. Ensure that the medication is kept out of reach of children and pets. Follow the storage instructions provided with the product to maintain its effectiveness and safety.

Oxiconazole Nitrate is applied topically to the affected skin areas. Clean and dry the area before application. Use the prescribed amount and gently rub it into the skin. Follow the application instructions provided by your physician to ensure effective treatment.

While rare, serious risks associated with Oxiconazole Nitrate include severe skin irritation, allergic reactions, and hyperpigmentation. If you experience any of these symptoms, discontinue use and notify your physician immediately. Always use the medication as directed and monitor for any adverse reactions.

Oxiconazole Nitrate should not be used by individuals who are allergic to oxiconazole nitrate or any of the inactive ingredients in the cream. If you have a known allergy or sensitivity, consult your physician before using this medication. Always inform your healthcare provider of any pre-existing conditions or medications you are taking.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

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