Oxomemazine Sans Sucre Sandoz Conseil (Oxomemazine)

Oxomemazine is a first‑generation H1‑receptor antagonist that acts on allergic pathways to reduce histamine‑mediated symptoms.

• Allergic rhinitis: alleviates nasal congestion, itching and sneezing.
• Acute urticaria: reduces wheal formation and itching.
• Cough associated with upper respiratory tract infections: suppresses the cough reflex.
• Motion sickness prophylaxis: helps prevent nausea and vomiting related to motion.
• Sedation before minor procedures: provides short‑term calming effect for patients undergoing minor diagnostic or therapeutic procedures.

• Oxomemazine blocks histamine H1 receptors in peripheral tissues and the central nervous system, preventing histamine from binding and triggering the cascade that leads to vasodilation, increased vascular permeability, and sensory nerve activation. This antagonism reduces allergic inflammation and exerts a sedative effect through central H1 blockade.

Oxomemazine may cause a range of adverse reactions, most of which are mild to moderate in intensity.

Common Side Effects

• Drowsiness: feeling ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​
• Dry mouth: reduced salivation leading to a dry sensation in the mouth.
• Dizziness: light‑headed feeling, especially when standing quickly.
• Blurred vision: temporary visual disturbances.
• Constipation: slowed gastrointestinal motility.
• Nausea: mild stomach upset.

Serious or Rare Side Effects

• Cardiac arrhythmias: irregular heart rhythm that may require medical attention.
• Severe allergic reaction: hives, swelling, or difficulty breathing.
• Extrapyramidal symptoms: involuntary muscle movements or tremor.
• Hepatotoxic  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​
• Blood dyscrasias  ​    ​    ​     ");