Oxycodone Depot Teva

Active Ingredient:: Oxycodone Hydrochloride
Origin:: EU

Oxycodone Depot Teva (Oxycodone Hydrochloride)

International sale not permitted. Listed for the domestic market and B2B only.

Oxycodone Hydrochloride, the active ingredient in Oxycodone Depot Teva, is an opioid analgesic presented as a depot formulation for oral use. It is indicated for the management of moderate to severe pain in adult patients who require continuous, long‑acting opioid therapy. GNH India supplies Oxycodone Depot Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

GNH India supplies Oxycodone Depot Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva Sweden Ab

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Indications & Clinical Uses

Oxycodone Depot Teva is an opioid analgesic that acts on the central nervous system to relieve pain.

Chronic cancer‑related pain: provides long‑acting analgesia for patients with persistent tumor‑associated pain.
Post‑surgical pain: maintains steady opioid levels after major surgery requiring extended pain control.
Severe non‑cancer chronic pain: offers continuous relief for conditions such as severe osteoarthritis when other treatments are insufficient.

How It Works

Oxycodone Hydrochloride binds selectively to mu‑opioid receptors in the central nervous system, activating these G‑protein‑coupled receptors. This activation reduces neuronal excitability and inhibits the transmission of nociceptive signals, producing analgesia while also affecting reward pathways that can influence perception of pain.

Side Effects

Oxycodone Depot Teva may cause a range of adverse reactions, from mild to potentially life‑threatening.

Common Side Effects

Constipation: reduced gastrointestinal motility leading to hard stools.
Nausea and vomiting: upset stomach often occurring early in therapy.
Drowsiness or sedation: increased sleepiness or reduced alertness.
Dry mouth: decreased salivary flow causing oral discomfort.
Itching or rash: mild skin irritation or pruritus.
Dizziness: sensation of light‑headedness or imbalance.

Serious or Rare Side Effects

Respiratory depression: slowed or shallow breathing that can be fatal.
Severe hypotension: marked drop in blood pressure leading to fainting.
Opioid use disorder: risk of dependence, tolerance, and addiction.
adrenal insufficiency: impaired cortisol production causing fatigue and weakness.
Seizures: rare occurrence of convulsive episodes.
Anaphylaxis: acute allergic reaction with airway compromise.

Precautions & Warnings

When prescribing Oxycodone Depot Teva, clinicians should consider several safety measures.

Assess pain severity and opioid tolerance: ensure the patient requires a long‑acting opioid.
Evaluate respiratory function: monitor for signs of respiratory depression, especially in opioid‑naïve individuals.
Review concomitant CNS depressants: avoid or limit use with benzodiazepines or alcohol.
Monitor for signs of dependence: watch for escalating dose requirements or drug‑seeking behavior.
Adjust for hepatic or renal impairment: dose may need modification in patients with liver or kidney disease.
Store at ambient temperature: keep below 25°C in the original packaging, protected from moisture.

Avoid Interactions

Oxycodone Depot Teva can interact with several medication classes, requiring careful management.

Major Interactions (Avoid)

Benzodiazepines: combined use can markedly increase risk of respiratory depression and profound sedation.
Central nervous system depressants: concurrent alcohol or barbiturates may amplify sedation and respiratory effects.
CYP3A4 inhibitors (e.g., ketoconazole, erythromycin): may raise oxy‑hydroxyhyd .

Moderate Interactions (Monitor Closely)

CYP3A4 inducers: rifampin .
Antidepressants (SSRIs, SNRIs): may increase serotonin levels and risk of serotonin syndrome.
Antihistamines: additive sedation.
Diuretics: may enhance hypotensive effects.
Anticonvulsants: may alter seizure threshold.

Frequently Asked Questions

Oxycodone Depot Teva is prescribed for the management of moderate to severe pain that requires continuous, long‑acting opioid therapy. It is commonly used in chronic cancer‑related pain, post‑surgical pain, and severe non‑cancer chronic pain when other analgesics are insufficient.

Oxycodone hydrochloride acts as an agonist at mu‑opioid receptors in the central nervous system. By activating these receptors, it reduces neuronal excitability and blocks the transmission of pain signals, providing analgesia while also influencing reward pathways that affect pain perception.

The specific dose of Oxycodone Depot Teva is determined by the prescribing clinician based on the patient’s pain severity, prior opioid exposure, and individual health factors. Dosage adjustments are made to achieve effective pain control while minimizing adverse effects.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 10 Oct 2026

Disclaimer

International sale not permitted. Listed for the domestic market and B2B only.

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