Product image of Ozalin (Midazolam) supplied by GNH India

Ozalin

Active Ingredient:
Midazolam
Origin:
EU

Ozalin (Midazolam)

Midazolam, the active ingredient in Ozalin, is a benzodiazepine presented as a strength/form for parenteral use. It is employed for sedation, anxiolysis, and seizure control in hospital settings. GNH India supplies Ozalin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

GNH India supplies Ozalin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Istituto Gentili S.R.L

1
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Indications & Clinical Uses

Midazolam is a short‑acting benzodiazepine that acts on the central nervous system to produce sedation and anxiolysis.

  • Pre‑operative sedation: facilitates calmness and amnesia before surgery.
  • Procedural sedation: provides rapid onset sedation for diagnostic or minor therapeutic procedures.
  • Status epilepticus: helps terminate ongoing seizures when rapid control is needed.
  • Intensive care unit sedation: maintains a controllable level of sedation for mechanically ventilated patients.
  • Anxiolysis in acute settings: reduces severe anxiety episodes in emergency or peri‑procedural contexts.

How It Works

  • Midazolam binds to the gamma‑aminobutyric acid (GGAA)‑A receptor complex, enhancing the inhibitory effect of GABA neurotransmission. This increased chloride ion influx hyperpolarises neuronal membranes, leading to reduced neuronal excitability, sedation, anxiolysis, amnesia, and anticonvulsant activity.

Side Effects

Midazolam may exhibit several adverse reactions that vary in frequency and severity.

Common Side Effects

  • Drowsiness
  • Dizziness
  • Headache
  • Nausea
  • Mild respiratory depression
  • Hypotension

Serious or Rare Side Effects

  • Severe respiratory depression
  • Paradoxical agitation or aggression
  • Cardiac arrhythmias
  • Anaphylaxis
  • Persistent amnesia
  • Withdrawal seizures

Precautions & Warnings

When using Midazolam, several precautions should be considered to ensure safe administration.

  • Patient assessment: evaluate  
  • Monitoring:  
  • Contra‑  
  • Drug‑  
  • Store  

Avoid Interactions

  • Midazole  
  • ---
  •   
  •   

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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