Product image of Ozarium (Losartan Potassium) supplied by GNH India

Ozarium

Active Ingredient:
Losartan Potassium
Origin:
EU

Ozarium (Losartan Potassium)

Losartan potassium, the active ingredient in Ozarium, is an angiotensin II receptor blocker (ARB) presented as a tablet for oral use. It is used to manage hypertension and protect kidney function in certain patients. GNH India supplies Ozarium as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

GNH India supplies Ozarium as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Anfarm Hellas Sa

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Indications & Clinical Uses

Losartan potassium is an ARB that modulates the renin‑angiotensin system to control blood pressure and related conditions.

  • Hypertension: helps lower elevated blood pressure and reduce cardiovascular risk.
  • Diabetic nephropathy: slows progression of kidney damage in patients with type 2 diabetes.
  • Heart failure: assists in managing symptoms and improving outcomes in certain heart‑failure patients.

How It Works

  • Losartan potassium selectively blocks the binding of angiotensin II to the AT‑1 receptor on vascular smooth‑muscle and adrenal cells. This inhibition prevents vasoconstriction and aldosterone release, leading to vasodilation, reduced sodium and water retention, and ultimately lower blood pressure.

Side Effects

Losartan potassium may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Dizziness
  • Headache
  • Fatigue
  • Nasal congestion
  • Upper respiratory tract infection
  • Diarrhea

Serious or Rare Side Effects

  • Hyperkalemia
  • Acute kidney injury
  • Angio‑edema
  • Severe hypotension
  • Liver enzyme elevation
  • Myocardial infarction in rare cases

Precautions & Warnings

When prescribing Losartan potassium, clinicians should consider several safety aspects.

  • Blood pressure monitoring: ensure adequate control and avoid excessive drops.
  • Renal function assessment: evaluate baseline kidney function and monitor periodically.
  • Electrolyte balance: check serum potassium, especially in patients on potassium‑sparing diuretics.
  • Pregnancy: avoid use in the second and third trimesters due to fetal toxicity.
  • Drug‑specific contraindications: review patient history for known hypersensitivity.
  • Store at below 25°C: keep in the original packaging, protect from moisture and light.

Avoid Interactions

Lostablet interacts with several medicines that can alter its efficacy or safety profile.

Major Interactions (Avoid)

  • Potassium‑rich supplements or salts: may cause dangerous hyper‑kalemia.
  • Aliskiren (in diabetic patients): combined use can increase risk of renal impairment.
  • Strong CYP3A4 inhibitors (e.g., itraconazole): may raise losartan levels.

Moderate Interactions (Monitor Closely)

  • Diuretics (especially thiazides): can enhance hypotensive effect.
  • NSAIDs: may blunt antihy‑hypertensive response and affect renal function.
  • Lithium: concurrent use can increase lithium concentrations.

Frequently Asked Questions

Ozarium contains losartan potassium, an angiotensin II receptor blocker that is prescribed to lower high blood pressure, protect kidney function in people with type 2 diabetes, and aid in the management of certain forms of heart failure.

Losartan potassium blocks the AT‑1 receptors that bind angiotensin II, preventing the hormone from causing blood‑vessel narrowing and aldosterone release. This results in relaxed blood vessels, reduced fluid retention and lower blood pressure.

The dose of Ozarium is individualized by a prescriber based on the patient’s blood‑pressure goals, kidney function and other clinical factors. Only a qualified health‑care professional should determine the appropriate regimen.

Losartan potassium is not recommended in the second or third trimester of pregnancy because it can harm the developing fetus. Limited data exist for breastfeeding, so the benefits and risks should be evaluated by a health‑care provider.

To order, submit an enquiry on the Ozarium product page at gnhindia.com, providing the required quantity and your institutional credentials. GNH India works with hospitals, pharmacies and procurement teams worldwide, then replies with pricing, availability, shipping details and any necessary import documentation.

Ozarium (losartan) is one of several ARBs; it shares the class‑wide benefit of blocking angiotensin II receptors but differs in dosing frequency, half‑life and specific evidence for kidney protection. Clinicians may choose losartan over alternatives based on patient comorbidities, tolerability and guideline recommendations.

Store Ozarium tablets at temperatures below 25 °C in the original container, protecting them from moisture and direct light. Do not use the product if the packaging is damaged or the tablets appear discoloured.

Ozarium is taken orally, usually once daily, with or without food. Patients should follow the prescribing clinician’s instructions regarding timing and whether the tablet should be swallowed whole or split.

Serious adverse events can include hyperkalemia, acute kidney injury, angio‑edema and severe hypotension. Patients should seek immediate medical attention if they experience swelling of the face or throat, rapid heartbeat, dizziness, or unexplained weakness.

Ozarium is contraindicated in individuals with known hypersensitivity to losartan or any ARB, in patients with severe liver impairment, and in pregnant women during the second and third trimesters. Caution is also advised for those with significant renal dysfunction.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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