Pamorelin LA 3.75mg (Triptorelin Powder) 3.75mg

Pamorelin LA 3.75mg is a prescription medication containing the active ingredient Triptorelin, formulated as a powder for prolonged-release suspension for intramuscular injection. It belongs to the drug class of gonadotropin-releasing hormone (GnRH) agonists, which function by suppressing the production of certain sex hormones. This therapeutic action helps manage hormone-dependent conditions under strict medical supervision.

Strength

3.75mg

Pack Size

Storage

Ambient

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Indications & Clinical Uses

Pamorelin LA 3.75mg is indicated for several hormone-sensitive conditions. Its primary therapeutic uses include the palliative treatment of advanced hormone-dependent prostate cancer, the management of endometriosis, the reduction of uterine fibroids size prior to surgery, and the treatment of central precocious puberty in children.

Side Effects

Common side effects of Pamorelin LA 3.75mg may include hot flashes, injection site pain, headache, mood changes, decreased libido, and erectile dysfunction. Some patients may experience a temporary increase in symptoms, known as a tumor flare, during the initial weeks of starting therapy.

Precautions & Warnings

This medication is classified under Pregnancy Category X and is strictly contraindicated in pregnant or breastfeeding women due to potential risk of fetal harm. Patients with a history of osteoporosis, cardiovascular disease, or severe depression should use Pamorelin LA with caution and under close clinical monitoring.

Avoid Interactions

Triptorelin may interact with other medications that affect gonadotropin secretion or drugs known to prolong the QT interval. It is essential to inform healthcare providers of all concurrent medications, including over-the-counter drugs and herbal supplements, to prevent adverse drug interactions.

Frequently Asked Questions

Pamorelin LA 3.75mg is primarily used to treat advanced prostate cancer, endometriosis, uterine fibroids, and central precocious puberty by suppressing the body's production of sex hormones.

Pamorelin LA 3.75mg is administered as an intramuscular injection by a qualified healthcare professional, typically as a prolonged-release suspension.

No, Pamorelin LA 3.75mg is contraindicated during pregnancy (Pregnancy Category X) as it can cause significant harm to an unborn fetus.

Common side effects include hot flashes, sweating, injection site reactions, fatigue, mood swings, and a temporary worsening of symptoms during the first few weeks of treatment.

It acts as a GnRH agonist, initially stimulating but ultimately down-regulating GnRH receptors, which suppresses the secretion of gonadotropins and lowers testosterone or estrogen to castrate levels.

Published by GNH India Pharmaceuticals Limited

Last updated: 17 Jun 2026

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