Product image of Panadol With Caffeine (Paracetamol, Caffeine) supplied by GNH India

Panadol With Caffeine

Active Ingredient:
Paracetamol, Caffeine
Origin:
EU

Panadol With Caffeine (Paracetamol, Caffeine)

Paracetamol, the active ingredient in Panadol With Caffeine, is an analgesic presented as a tablet for oral use. It treats mild to moderate pain and reduces fever in adults and children. Caffeine acts as a central nervous system stimulant that can enhance the analgesic effect of paracetamol.

GNH India supplies Panadol With Caffeine as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Haleon Ireland Limited

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Indications & Clinical Uses

Panadol With Caffeine combines paracetamol and caffeine to relieve pain and fever through a dual‑action pathway.

  • Headache: Reduces intensity and improves alertness during tension‑type headaches.
  • Dental pain: Alleviates post‑extraction or procedural discomfort.
  • Musculoskeletal pain: Diminishes aches associated with minor sprains, strains and backache.
  • Fever: Lowers elevated body temperature in acute febrile episodes.
  • Cold‑related discomfort: Relieves sinus pressure and headache associated with common colds.

How It Works

  • Paracetamol inhibits cyclo‑oxygenase enzymes in the central nervous system, reducing prostaglandin synthesis and thereby lowering pain perception and fever. Caffeine antagonises adenosine receptors, producing mild central stimulation and enhancing the analgesic effect of paracetamol by increasing its absorption and potency.

Side Effects

Adverse reactions to Panadol With Caffeine are generally mild but can vary in frequency.

Common Side Effects

  • Nausea: Mild stomach upset or queasiness.
  • Gastric discomfort: Minor indigestion or abdominal pain.
  • Insomnia: Difficulty falling or staying asleep, especially if taken later in the day.
  • Restlessness: Feeling of unease or jitteriness.
  • Increased heart rate: Slight tachycardia without other cardiac symptoms.

Serious or Rare Side Effects

  • Allergic reaction: Hives, swelling, or difficulty breathing.
  • Liver toxicity: Elevated liver enzymes or hepatic failure with overdose.
  • Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Anaphylaxis: Rapid onset of systemic allergic response requiring emergency care.

Precautions & Warnings

When using Panadol With Caffeine, consider the following safety measures.

  • Liver disease: Avoid use or limit dose in patients with hepatic impairment.
  • Alcohol consumption: Limit alcohol intake as it may increase liver risk.
  • Pregnancy: Use only if clearly indicated and prescribed by a healthcare professional.
  • Breastfeeding: Consult a physician before use while nursing.
  • Children: Do not give to children under the recommended age without medical advice.
  • Store at ambient temperature: Keep below 25 °C, in the original packaging, protected from moisture.

Avoid Interactions

Panadol With Caffeine may interact with several medicines; monitoring is advised.

Major Interactions (Avoid)

  • Warfarin: Increased risk of bleeding due to enhanced anticoagulant effect.
  • Carbamazepine: Accelerated metabolism of paracetamol, reducing efficacy.
  • Rifampicin: Induces hepatic enzymes, lowering paracetamol plasma levels.

Moderate Interactions (Monitor Closely)

  • Antidepressants (SSRIs, SNRIs): May increase risk of serotonin syndrome.
  • Diuretics: Potential for altered caffeine clearance.
  • Beta‑blockers: May blunt caffeine‑induced tachycardia but require observation.

Frequently Asked Questions

Panadol With Caffeine is formulated to provide relief from mild to moderate pain such as headache, dental discomfort, musculoskeletal aches, and to reduce fever. The combination of paracetamol and caffeine offers both analgesic and central‑stimulating effects, helping to improve pain control and alertness.

Paracetamol acts primarily in the central nervous system by inhibiting cyclo‑oxygenase enzymes, which lowers prostaglandin production. This reduction diminishes pain signals and resets the hypothalamic set‑point for temperature, resulting in analgesia and antipyresis.

The appropriate dose of Panadol With Caffeine is determined by a prescriber based on the patient’s age, weight, clinical condition, and local regulatory guidelines. Patients should follow the specific instructions provided by their healthcare professional.

Paracetamol is generally considered safe in pregnancy when used at recommended doses, but caffeine exposure should be limited. Breastfeeding mothers should consult a healthcare professional, as small amounts of both ingredients can pass into breast milk.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

The addition of caffeine to paracetamol can enhance analgesic efficacy, particularly for headache and fatigue‑related pain, by increasing central nervous system stimulation and improving drug absorption. Regular paracetamol lacks this stimulant effect, which may result in slower onset of relief for certain conditions.

Store tablets at ambient temperature, preferably below 25 °C, in the original container to protect from moisture and light. Keep out of reach of children and avoid storing in humid or excessively hot environments.

Panadol With Caffeine is taken orally, usually with a glass of water. It should be swallowed whole and not crushed or chewed unless the product label specifically permits it.

Serious risks include severe allergic reactions such as anaphylaxis, liver toxicity from overdose, and rare skin conditions like Stevens‑Johnson syndrome. Immediate medical attention is required if any of these symptoms appear.

Individuals with known hypersensitivity to paracetamol or caffeine, severe liver disease, or those taking contraindicated medications such as certain anticoagulants should avoid this product unless advised otherwise by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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