Product image of Panmigrol Migraine Pain Relief (Paracetamol, Acetylsalicylic Acid, Caffeine) supplied by GNH India

Panmigrol Migraine Pain Relief

Active Ingredient:
Paracetamol, Acetylsalicylic Acid, Caffeine
Origin:
EU

Panmigrol Migraine Pain Relief (Paracetamol, Acetylsalicylic Acid, Caffeine)

Paracetamol, Acetylsalicylic Acid and Caffeine, the active ingredients in Panmigrol Migraine Pain Relief, are a combination analgesic presented as a fixed‑dose oral tablet for oral use. It is intended to relieve acute migraine attacks and other moderate to severe headache pain in adults.

GNH India supplies Panmigrol Migraine Pain Relief as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Manufacturer / TM Owner

Haleon Uk Trading Limited

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Indications & Clinical Uses

Panmigrol Migraine Pain Relief, a combination analgesic, is used to manage acute migraine and related headache disorders.

  • Migraine: provides rapid relief of moderate to severe migraine pain and associated symptoms.
  • Tension‑type headache: reduces pain intensity when other simple analgesics are insufficient.
  • Fever: lowers elevated body temperature associated with common viral infections.

How It Works

  • Paracetamol acts centrally to inhibit prostaglandin synthesis, reducing pain and fever. Acetylsalicylic acid irreversibly inhibits cyclooxygenase‑1 and cyclooxygenase‑2, decreasing peripheral prostaglandin production and platelet aggregation. Caffeine blocks adenosine receptors, enhancing analgesic potency and promoting vasoconstriction, which together accelerate the onset of pain relief in migraine episodes.

Side Effects

Panmigrol Migraine Pain Relief may cause a range of adverse reactions. Most are mild and reversible.

Common Side Effects

  • Nausea: mild gastrointestinal upset.
  • Gastric discomfort: transient indigestion.
  • Insomnia: difficulty falling asleep.
  • Restlessness: mild nervousness.
  • Dizziness: occasional light‑headedness.

Serious or Rare Side Effects

  • Allergic reaction: rash, itching, swelling, or anaphylaxis.
  • Gastrointestinal bleeding: black stools or vomiting blood.
  • Liver dysfunction: jaundice or elevated liver enzymes.
  • Severe hypertension: sudden increase in blood pressure.
  • Renal impairment: reduced urine output or swelling.

Precautions & Warnings

Before using Panmigrol Migraine Pain Relief, consider the following safety measures.

  • Pregnancy: avoid unless clearly indicated by a healthcare professional.
  • Breastfeeding: consult a physician as caffeine and aspirin may affect the infant.
  • Liver disease: use with caution; monitor hepatic function.
  • Bleeding disorders: assess risk due to aspirin component.
  • Asthma: watch for hypersensitivity reactions.
  • Store at ambient temperature: keep below 25°C, retain in original packaging, protect from moisture.

Avoid Interactions

Panmigrol Migraine Pain Relief can interact with several medicines; monitoring is essential.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Other NSAIDs (e.g., ibuprofen): heightened gastrointestinal toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): potential for hemorrhage.

Moderate Interactions (Monitor Closely)

  • Antihypertensives: caffeine may reduce efficacy.
  • Diuretics: aspirin may impair renal function.
  • Lithium: aspirin can increase lithium levels.
  • Methotrexate: aspirin may raise toxicity risk.

Frequently Asked Questions

Panmigrol Migraine Pain Relief is a fixed‑dose oral tablet that combines paracetamol, acetylsalicylic acid and caffeine to provide rapid relief of acute migraine attacks and other moderate to severe headaches in adults.

Paracetamol reduces pain and fever by acting on central prostaglandin pathways. Acetylsalicylic acid blocks cyclooxygenase enzymes, decreasing peripheral prostaglandin production and platelet aggregation. Caffeine antagonises adenosine receptors, enhancing analgesic effect and causing vasoconstriction, which together speed up migraine pain relief.

The appropriate dose is determined by the prescribing healthcare professional based on the patient’s condition, age, weight and other medications. Patients should follow the prescriber’s instructions and not exceed the recommended amount.

Use of this product during pregnancy is generally discouraged unless clearly indicated by a physician, due to the aspirin component. While breastfeeding, caution is advised because caffeine and aspirin can pass into breast milk; a healthcare professional should evaluate the risk‑benefit ratio.

Enquiries can be submitted via the product page on gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Panmigrol combines an analgesic (paracetamol), an NSAID (acetylsalicylic acid) and a stimulant (caffeine), offering a multi‑mechanistic approach. Compared with single‑agent triptans, it may be less effective for severe migraine but provides a non‑prescription option with a rapid onset for mild to moderate attacks.

Store the tablets at ambient temperature, preferably below 25 °C. Keep them in the original blister pack, protect from moisture and direct sunlight, and keep out of reach of children.

The product is taken orally with a full glass of water. It should be swallowed whole and not crushed or chewed, unless otherwise directed by a healthcare professional.

Serious risks include allergic reactions such as rash or anaphylaxis, gastrointestinal bleeding, liver dysfunction, severe hypertension, and renal impairment. Patients should seek immediate medical attention if they experience any of these symptoms.

Individuals with known hypersensitivity to paracetamol, aspirin, or caffeine, those with active peptic ulcer disease, bleeding disorders, severe liver or kidney disease, uncontrolled hypertension, or children under the recommended age should avoid this medication.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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