Product image of Panodil (Paracetamol) supplied by GNH India

Panodil

Active Ingredient:
Paracetamol
Origin:
EU

Panodil (Paracetamol)

Paracetamol, the active ingredient in Panodil, is an Analgesic presented as a tablet for oral use. It is used to relieve mild to moderate pain and to reduce fever in adults and children.
GNH India supplies Panodil as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Evolan Pharma Ab

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Indications & Clinical Uses

Paracetamol acts as an analgesic and antipyretic, addressing pain and fever pathways.

  • Pain: provides relief of mild to moderate pain such as headache, toothache, or muscle aches.
  • Fever: lowers elevated body temperature associated with infections or inflammatory conditions.
  • Post‑operative discomfort: helps manage discomfort after minor surgical procedures.

How It Works

  • Paracetamol exerts its effect by inhibiting the synthesis of prostaglandins in the central nervous system, primarily through reversible blockade of the cyclooxygenase (COX) enzymes. This reduction in prostaglandin production diminishes the perception of pain and resets the hypothalamic temperature set‑point, leading to antipyretic action without significant peripheral anti‑inflammatory activity.

Side Effects

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea: mild stomach upset or queasiness.
  • Skin rash: occasional mild erythema or itching.
  • Abdominal discomfort: transient stomach pain.
  • Elevated liver enzymes: mild, reversible changes in laboratory tests.
  • Headache: occasional mild headache.

Serious or Rare Side Effects

  • Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Hepatotoxicity: acute liver injury, especially with overdose or chronic high‑dose use.
  • Blood disorders: agranulocytosis or thrombocytopenia.
  • Anaphylaxis: rare but potentially life‑threatening allergic reaction.

Precautions & Warnings

Paracetamol should be used with awareness of specific safety considerations.

  • Dosage limits: adhere to maximum daily dose to avoid liver toxicity.
  • Alcohol consumption: limit intake as combined use increases hepatic risk.
  • Pre‑existing liver disease: use only under medical supervision.
  • Pregnancy and breastfeeding: consult a healthcare professional before use.
  • Drug interactions: review concomitant medications for potential interactions.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture.

Avoid Interactions

Paracetamol may interact with several medicines, requiring careful management.

Major Interactions (Avoid)

  • Alcohol: concurrent use heightens risk of liver injury.
  • Warfarin: may enhance anticoagulant effect, increasing bleeding risk.
  • Carbamazepine or phenytoin: enzyme inducers that can reduce paracetamol effectiveness.

Moderate Interactions (Monitor Closely)

  • Other hepatotoxic drugs: combined use may increase liver strain.
  • Isoniazid: may potentiate liver enzyme elevations.
  • High‑dose vitamin C: can alter paracetamol metabolism.
  • Certain antiviral agents: may affect plasma concentrations.

Frequently Asked Questions

Panodil contains paracetamol, which is used to relieve mild to moderate pain such as headaches, toothaches, muscle aches, and to reduce fever associated with infections or inflammatory conditions. It is an over‑the‑counter option for adults and children when a non‑opioid analgesic is appropriate.

Paracetamol works by inhibiting the central synthesis of prostaglandins through reversible blockade of cyclooxygenase enzymes. This action lowers the hypothalamic set‑point for temperature, producing antipyretic effects, and reduces the perception of pain without significant peripheral anti‑inflammatory activity.

The appropriate dose of Panodil is determined by a prescriber or according to the product label. Dosage depends on the patient’s age, weight, and clinical condition, and it should never exceed the maximum daily amount recommended for paracetamol.

Paracetamol is generally considered the analgesic of choice during pregnancy and lactation when needed, but safety information is limited. Women who are pregnant or breastfeeding should consult their healthcare provider before using Panodil to ensure it is appropriate for their specific situation.

To order Panodil, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide. After submission, the sales team will verify trade or institutional credentials and respond with pricing, availability, shipping details, and any necessary import documentation.

Panodil (paracetamol) differs from non‑steroidal anti‑inflammatory drugs (NSAIDs) such as ibuprofen in that it lacks significant peripheral anti‑inflammatory activity and does not increase gastrointestinal bleeding risk. It is also not an opioid, making it suitable for patients who need pain relief without opioid‑related side effects.

Panodil should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in their original packaging, protect them from moisture and direct sunlight, and ensure they are out of reach of children.

Panodil is taken orally, usually with a glass of water. It can be taken with or without food, but patients should follow the dosing instructions provided by their healthcare professional or the product label.

The most serious risks include severe liver injury, especially with overdose or chronic high‑dose use, and rare but life‑threatening skin reactions such as Stevens‑Johnson syndrome. Prompt medical attention is required if signs of liver dysfunction or severe skin rash develop.

Panodil should be avoided by individuals with known hypersensitivity to paracetamol, those with severe liver impairment, or patients who are regularly consuming excessive alcohol. It should also be used with caution in patients taking other hepatotoxic medications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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