Panoxyl Wash (Benzoyl Peroxide)

• Panoxyl Wash contains benzoyl peroxide, a keratolytic that acts on the skin to manage acne-related conditions.
• Acne vulgaris: reduces inflammatory lesions and prevents formation of new comedones.
• Comedonal acne: promotes desquamation of follicular epithelium to clear blocked pores.
• Inflammatory acne: decreases Propionibacterium acnes colonisation, limiting lesion development.

• Benzoyl peroxide releases oxygen free radicals that oxidize bacterial proteins, thereby reducing Propionibacterium acnes populations. Simultaneously, its keratolytic action loosens intercellular connections in the follicular epithelium, facilitating desquamation and preventing pore blockage.

Panoxyl Wash may cause skin reactions, most of which are mild and reversible.

Common Side Effects

• Skin irritation or redness
• Dryness or peeling of the treated area
• Mild itching or burning sensation
• Temporary tingling feeling
• Increased sensitivity to sunlight
• Minor scaling or flaking

Serious or Rare Side Effects

• Severe allergic reaction (e.g., urticaria, angioedema)
• Contact dermatitis with extensive swelling
• Persistent or worsening erythema
• Bullous skin lesions
• Systemic hypersensitivity requiring medical attention
• Unusual discoloration of hair or skin

When using Panoxyl Wash, consider the following safety measures.

• Sun exposure: limit direct UV exposure and use sunscreen, as the product can increase photosensitivity.
• Moisturization: apply a non‑comedogenic moisturizer after washing to reduce dryness.
• Combination therapy: avoid simultaneous use of other strong keratolytics or retinoids without professional guidance.
• Irritation monitoring: discontinue use and seek medical advice if severe irritation develops.
• Eye contact: avoid contact with eyes; rinse thoroughly with water if accidental exposure occurs.
• Store at ambient temperature: keep in the original container, protect from moisture and excessive heat.

Benzoyl peroxide may interact with other topical or systemic agents.

Major Interactions (Avoid)

• Concurrent use with other benzoyl peroxide products, which can cause excessive dryness.
• Combination with topical retinoids without staggered application, increasing irritation risk.
• Use with strong photosensitizing agents, heightening sun sensitivity.

Moderate Interactions (Monitor Closely)

• Oral tetracycline antibiotics, which may augment photosensitivity.
• Topical corticosteroids, potentially reducing the wash's efficacy.
• Other keratolytic agents (e.g., salicylic acid) that may increase local irritation.
• Antifungal creams applied to the same area, possibly altering skin barrier function.
• Use with cosmetic peels or abrasive scrubs, requiring careful monitoring for skin integrity.