Product image of Pansoral (Choline Salicylate, Cetalkonium Chloride) supplied by GNH India

Pansoral

Active Ingredient:
Choline Salicylate, Cetalkonium Chloride
Origin:
EU

Pansoral (Choline Salicylate, Cetalkonium Chloride)

Choline Salicylate and Cetalkonium Chloride, the active ingredient in Pansoral, is a NSAID and antiseptic presented as an oral dosage form for oral use. It provides symptomatic relief of sore throat and oral mucosal inflammation in adults and children.

GNH India supplies Pansoral as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Pierre Fabre Medicament

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Indications & Clinical Uses

Pansoral, containing choline salicylate and cetalkonium chloride, is used to manage inflammatory and infectious conditions of the oral cavity.

  • Sore throat: reduces pain and inflammation in the pharyngeal mucosa.
  • Oral mucosal inflammation: alleviates swelling and discomfort in inflamed oral tissues.
  • Oral infections: provides antiseptic action to help control microbial growth in the mouth.

How It Works

  • Choline salicylate inhibits cyclooxygenase enzymes, decreasing prostaglandin synthesis and thereby reducing inflammation and pain. Cetalkonium chloride acts as a cationic antiseptic, disrupting microbial cell membranes and limiting bacterial colonisation in the oral cavity. The combined actions provide both analgesic and antimicrobial effects when applied locally.

Side Effects

Common Side Effects

  • Altered taste: transient metallic or bitter sensation in the mouth.
  • Mild nausea: occasional stomach upset after administration.
  • Oral irritation: transient burning or tingling at the site of contact.
  • Dyspepsia: mild indigestion or heartburn.

Serious or Rare Side Effects

  • Allergic reactions: rash, itching, swelling, or difficulty breathing.
  • Severe gastrointestinal bleeding: black stools or vomiting of blood.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis: severe skin blistering and mucosal involvement.

Precautions & Warnings

Before using Pansoral, consider the following precautions:

  • Assess allergy history: avoid if known hypersensitivity to salicylates or cetalkonium chloride.
  • Monitor for gastrointestinal irritation: advise patients to report persistent stomach pain or bleeding.
  • Use with caution in children: follow pediatric dosing guidance and avoid excessive use.
  • Avoid concurrent anticoagulants: increased risk of bleeding when combined with warfarin or similar agents.
  • Store at ambient temperature below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Pansoral may interact with other medicines as follows:

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Other NSAIDs or salicylates: additive gastrointestinal toxicity.
  • Methotrexate: reduced renal clearance may increase toxicity.

Moderate Interactions (Monitor Closely)

  • Corticosteroids: heightened risk of gastrointestinal ulceration.
  • Selective serotonin reuptake inhibitors (SSRIs): potential for increased bleeding.

Frequently Asked Questions

Pansoral is an over‑the‑counter oral product that combines choline salicylate and cetalkonium chloride to relieve pain and inflammation associated with sore throat and other oral mucosal irritations. It also provides local antiseptic activity to help control bacterial growth in the mouth.

Choline salicylate belongs to the non‑steroidal anti‑inflammatory drug (NSAID) class. It blocks cyclooxygenase enzymes, which reduces the synthesis of prostaglandins—key mediators of pain, swelling and fever—thereby providing analgesic and anti‑inflammatory effects at the site of application.

The appropriate dose of Pansoral is determined by the prescribing healthcare professional based on the patient’s age, severity of symptoms and overall health status. Patients should follow the prescriber’s instructions and the product label without exceeding the recommended frequency.

Safety data for Pansoral in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should consult their physician before using the product to weigh potential benefits against any unknown risks.

To order Pansoral, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Unlike many lozenges that contain only a single analgesic, Pansoral combines an NSAID (choline salicylate) with an antiseptic (cetalkonium chloride). This dual action offers both pain relief and antimicrobial activity, which can be advantageous when a sore throat is accompanied by mild infection.

Pansoral should be stored at ambient temperature below 25 °C, in its original packaging, and protected from moisture. Keep the product out of reach of children and avoid exposing it to direct sunlight or extreme humidity.

Pansoral is taken orally, typically as a lozenge or dissolved tablet, allowing the active ingredients to act directly on the oral mucosa. Patients should allow the product to dissolve slowly in the mouth and avoid swallowing whole tablets before they have dissolved.

Serious adverse reactions, although rare, include severe allergic responses such as rash, swelling, or difficulty breathing, and gastrointestinal bleeding. If any signs of a severe reaction appear, the user should stop the product immediately and seek medical attention.

Individuals with a known hypersensitivity to salicylates, cetalkonium chloride, or any component of the formulation should avoid Pansoral. It is also contraindicated in patients taking anticoagulant therapy, other NSAIDs, or those with active gastrointestinal ulceration unless directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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