Product image of Pantenol Labesfal (Dexpanthenol) supplied by GNH India

Pantenol Labesfal

Active Ingredient:
Dexpanthenol
Origin:
EU

Pantenol Labesfal (Dexpanthenol)

Dexpanthenol, the active ingredient in Pantenol Labesfal, is a vitamin B5 derivative presented as a topical cream for dermal use. It supports skin barrier restoration and promotes healing of minor injuries and irritations.\n\nGNH India supplies Pantenol Labesfal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Labesfal Laboratorios Almiro, S.A.

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Indications & Clinical Uses

  • Dexpanthenol is applied to skin conditions where barrier repair and tissue regeneration are required.\n\n- Dermatitis: helps restore the epidermal barrier and reduces inflammation.\n- Minor burns: accelerates wound healing and alleviates pain.\n- Post‑operative wound care: supports tissue regeneration and reduces scar formation.

How It Works

  • Dexpanthenol is rapidly converted to pantothenic acid (vitamin B5) within skin cells, where it participates in co‑enzyme A synthesis. This enhances fatty acid metabolism, promotes keratinocyte proliferation, and improves the synthesis of structural lipids, leading to accelerated epidermal regeneration and improved barrier function.

Side Effects

  • Adverse reactions to topical Dexpanthenol are generally mild but can occur.\n\nCommon Side Effects:\n- Mild skin irritation at the application site.\n- Transient erythema or redness.\n- Pruritus or itching.\n- Dryness or peeling of the treated area.\n- Sensation of warmth or tingling.\n\nSerious or Rare Side Effects:\n- Allergic contact dermatitis with swelling and intense itching.\n- Severe hypersensitivity reaction, including urticaria or angioedema.\n- Systemic toxicity (extremely rare) manifested by nausea or dizziness when applied over large broken skin areas.

Precautions & Warnings

  • When using Dexpanthenol, consider the following safety measures.\n\n- Pregnancy: consult a healthcare professional before use.\n- Breastfeeding: use with caution and under medical advice.\n- Known allergy to Dexpanthenol or related compounds: avoid application.\n- Application on extensive broken skin: monitor for possible systemic absorption.\n- Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

  • Dexpanthenol has a low interaction profile, but certain combinations may require attention.\n\nMajor Interactions (Avoid):\n- Concurrent use with potent topical corticosteroids: may diminish the healing benefit of Dexpanthenol.\n- Application together with strong antiseptic agents (e.g., povidone‑iodine): can cause irritation.\n\nModerate Interactions (Monitor Closely):\n- Use with other wound‑healing agents (e.g., silver sulfadiazine): monitor for additive irritation.\n- Systemic vitamin B5 supplements: generally safe but observe for any unexpected effects.\n- Combination with occlusive dressings: may increase local absorption, watch for skin reactions.

Frequently Asked Questions

Pantenol Labesfal contains Dexpanthenol, a vitamin B5 derivative that is applied topically to support skin barrier repair, accelerate healing of minor burns, dermatitis, and to aid post‑operative wound care. It helps restore moisture and promotes tissue regeneration in superficial skin injuries.

After application, Dexpanthenol is converted to pantothenic acid within skin cells, contributing to co‑enzyme A production. This enhances fatty acid metabolism, keratinocyte proliferation, and the synthesis of structural lipids, which together speed up epidermal regeneration and improve barrier function.

The dosage of Pantenol Labesfal is determined by the prescribing healthcare professional based on the specific indication, size of the area to be treated, and patient factors. The product is typically applied as a thin layer to the affected skin as directed by the prescriber.

Pregnant or breastfeeding individuals should consult their healthcare provider before using Pantenol Labesfal. While topical Dexpanthenol is generally considered low risk, professional guidance ensures appropriate use and monitoring for any potential concerns.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide. After submission, the sales team will verify trade or institutional credentials and respond with pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Compared with other topical agents such as silver sulfadiazine or corticosteroid creams, Pantenol Labesfal offers a vitamin‑based mechanism that promotes natural skin regeneration without the antimicrobial or anti‑inflammatory potency of those alternatives. It is generally well‑tolerated and suitable for mild to moderate skin injuries where barrier restoration is the primary goal.

Store Pantenol Labesfal at room temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Pantenol Labesfal is applied topically to clean, dry skin. A thin, even layer should be spread over the affected area, usually once or twice daily, or as directed by the prescribing clinician. Do not cover with occlusive dressings unless advised.

The most serious risks involve allergic reactions such as contact dermatitis, urticaria, or angioedema. In rare cases, extensive application on large broken skin may lead to systemic absorption and symptoms like nausea or dizziness. Prompt medical attention is required if severe reactions occur.

Individuals with a known hypersensitivity to Dexpanthenol or any component of the formulation should avoid using the product. It is also contraindicated on severely infected wounds without medical supervision and should be used cautiously in pregnant or breastfeeding women without professional advice.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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