Product image of Pantoprazol Braiter (Pantoprazole) supplied by GNH India

Pantoprazol Braiter

Active Ingredient:
Pantoprazole
Origin:
EU

Pantoprazol Braiter (Pantoprazole)

Pantoprazole, the active ingredient in Pantoprazol Brauer, is a proton pump inhibitor presented as a tablet for oral use. It reduces stomach acid production and is used to treat acid‑related gastrointestinal conditions in adults and children.
GNH India supplies Pantoprazol Brauer as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Pentafarma - Sociedade Tecnico-Medicinal S.A.

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Indications & Clinical Uses

Pantoprazol Brauer is a proton pump inhibitor that acts on the gastric acid secretion pathway. It is indicated for several acid‑related disorders:

  • Gastro‑esophageal reflux disease (GERD): alleviates heartburn and promotes healing of the esophageal lining.
  • Erosive esophagitis: heals erosions and reduces further damage.
  • Zollinger‑Ellison syndrome: controls excessive gastric acid production associated with this rare endocrine disorder.

How It Works

  • Pantoprazole selectively inhibits the H+/K+‑ATPase enzyme (the gastric proton pump) located on the secretory surface of parietal cells. By binding covalently to the pump’s cysteine residues, it blocks the final step of acid secretion, leading to a sustained increase in gastric pH and reduced acidity in the stomach.

Side Effects

Pantoprazol Brauer is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Diarrhea: usually self‑limiting.
  • Nausea: occasional and transient.
  • Abdominal pain: mild discomfort.
  • Flatulence: increased gas.
  • Constipation: infrequent.

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis): rash, swelling, difficulty breathing.
  • Clostridioides difficile infection: persistent watery diarrhea.
  • Low magnesium levels (hypomagnesemia): muscle cramps, irregular heartbeat.
  • Bone fractures: increased risk with long‑term use.
  • Acute interstitial nephritis: kidney inflammation.
  • Liver enzyme elevation: signs of hepatic stress.

Precautions & Warnings

When prescribing Pantoprazol Brauer, consider the following safety measures:

  • Assess renal function: adjust use in severe impairment.
  • Monitor magnesium levels: especially during prolonged therapy.
  • Evaluate bone health: consider calcium/vitamin D supplementation for long‑term users.
  • Review concomitant medications: potential for altered absorption of drugs requiring acidic pH.
  • Pregnancy and lactation: use only if clearly needed after risk‑benefit assessment.
  • Store at below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Pantoprazol Brauer may affect the pharmacokinetics of several co‑administered drugs.

Major Interactions (Avoid)

  • Antifungal azoles (ketoconazole, itraconazole): reduced absorption and efficacy.
  • HIV protease inhibitors (ritonavir, atazanavir): decreased plasma concentrations.

Moderate Interactions (Monitor Closely)

  • Antiplatelet agents (clopidogrel): possible reduction in antiplatelet effect.
  • Warfarin: potential alteration of INR values.
  • Methotrexate: increased systemic exposure, especially at high doses.
  • Digoxin: modest increase in serum levels.
  • Iron supplements: decreased absorption; separate dosing by at least 2 hours.

Frequently Asked Questions

Pantoprazol Brauer contains pantoprazole, a proton pump inhibitor that is prescribed for acid‑related gastrointestinal disorders such as gastro‑esophageal reflux disease (GERD), erosive esophagitis and Zollinger‑Ellison syndrome. It works by lowering stomach acidity, which helps relieve symptoms and promotes healing of the esophageal lining.

Pantoprazole blocks the H+/K+‑ATPase enzyme, commonly called the gastric proton pump, on the surface of stomach parietal cells. By irreversibly inhibiting this pump, it prevents the final step of acid secretion, leading to a sustained rise in gastric pH and reduced acidity that alleviates acid‑related damage.

The dosage of Pantoprazol Brauer is determined by the prescribing clinician based on the specific indication, patient age, renal function and treatment duration. Healthcare professionals set the appropriate strength and dosing schedule according to clinical guidelines and individual patient needs.

Pantoprazole is classified as pregnancy category B in many regions, indicating no evidence of risk in animal studies but limited human data. It should be used during pregnancy or lactation only if the potential benefit justifies the potential risk, and the decision should be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Pantoprazol Brauer belongs to the proton pump inhibitor class, which provides more potent and longer‑lasting acid suppression than H2‑receptor antagonists such as ranitidine. Compared with other PPIs, pantoprazole has a lower potential for drug‑drug interactions mediated by CYP2C19, making it a suitable option for patients on multiple medications.

Store Pantoprazol Brauer tablets at temperatures below 25 °C in their original container, protected from moisture, heat and direct sunlight. Maintaining these conditions preserves the tablet’s stability and potency throughout its shelf life.

Pantoprazol Brauer is supplied as oral tablets that are taken with water. For optimal absorption, it is usually recommended to swallow the tablet whole, preferably before a meal, unless the prescribing clinician advises an alternative administration schedule.

Serious risks, though uncommon, include severe allergic reactions (anaphylaxis), Clostridioides difficile‑associated diarrhea, low magnesium levels, acute interstitial nephritis and increased risk of bone fractures with long‑term use. Patients should seek immediate medical attention if they experience symptoms such as rash, persistent diarrhea, muscle cramps or unexplained bone pain.

Pantoprazol Brauer is contraindicated in individuals with known hypersensitivity to pantoprazole or any other component of the formulation. Caution is also advised for patients with severe liver impairment, those taking certain interacting medications, and pregnant or breastfeeding women unless the benefits outweigh the risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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