Product image of Pantoprazol Davur (Pantoprazole) supplied by GNH India

Pantoprazol Davur

Active Ingredient:
Pantoprazole
Origin:
EU

Pantoprazol Davur (Pantoprazole)

Pantoprazole, the active ingredient in Pantoprazol Davur, is a proton pump inhibitor presented as a 40 mg tablet for oral use. It reduces stomach acid production and is used to treat gastro‑intestinal conditions such as GERD in adult patients.
GNH India supplies Pantoprazol Davur as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva Pharma S.L.U.,

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Indications & Clinical Uses

Pantoprazol Davur is a proton pump inhibitor that acts on the acid‑secretion pathway of the stomach. It is indicated for several gastrointestinal disorders:

  • Gastro‑oesophageal reflux disease (GERD): provides symptomatic relief of heartburn and promotes healing of erosive esophagitis.
  • Erosive esophagitis: accelerates mucosal healing and reduces risk of complications.
  • Zollinger‑Ellison syndrome: controls excessive gastric acid secretion associated with gastrin‑producing tumours.

How It Works

  • Pantoprazole selectively inhibits the H+/K+‑ATPase enzyme (the gastric proton pump) located on the parietal cell surface of the stomach lining. By binding covalently to the pump’s cysteine residues, it blocks the final step of acid secretion, leading to a sustained increase in gastric pH and reduced acidity in the gastrointestinal tract.

Side Effects

Pantoprazol Davur may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Diarrhoea: watery stools without blood.
  • Nausea: occasional feeling of stomach upset.
  • Abdominal pain: cramp‑like discomfort.
  • Flatulence: increased intestinal gas.
  • Constipation: infrequent, hard stools.

Serious or Rare Side Effects

  • Severe allergic reaction: rash, itching, swelling, or difficulty breathing.
  • Clostridioides difficile infection: persistent watery diarrhoea, fever, abdominal pain.
  • Low magnesium levels: muscle cramps, irregular heartbeat, seizures.
  • Bone fractures: increased risk with long‑term use.
  • Liver enzyme elevation: jaundice, dark urine, fatigue.
  • Acute interstitial nephritis: reduced urine output, flank pain, swelling.

Precautions & Warnings

Before initiating therapy with Pantoprazol Davur, consider the following safety measures:

  • Assess renal function: adjust dosing in severe renal impairment.
  • Review concomitant medications: evaluate for potential drug‑drug interactions.
  • Monitor magnesium levels: especially during prolonged therapy.
  • Evaluate bone health: consider calcium and vitamin D supplementation for long‑term users.
  • Pregnancy and lactation: use only if clearly needed after risk‑benefit assessment.
  • Store at below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Pantoprazol Davur can affect the pharmacokinetics of several co‑administered drugs. Interaction management is essential for patient safety.

Major Interactions (Avoid)

  • Ketoconazole oral suspension: markedly reduced antifungal absorption.
  • Atazanavir: substantially decreased antiviral efficacy.
  • Clopidogrel: diminished antiplatelet activity, increasing cardiovascular risk.

Moderate Interactions (Monitor Closely)

  • Warfarin: potential alteration of INR values; monitor coagulation.
  • Methotrexate: increased systemic exposure; check renal function and drug levels.
  • Digoxin: slight increase in serum concentrations; observe for toxicity signs.

Frequently Asked Questions

Pantoprazol Davur contains pantoprazole, a proton pump inhibitor that is prescribed for acid‑related gastrointestinal disorders such as gastro‑oesophageal reflux disease (GERD), erosive esophagitis and Zollinger‑Ellison syndrome. It works by lowering stomach acidity, which helps relieve symptoms and promotes healing of the esophageal lining.

Pantoprazole selectively blocks the gastric H+/K+‑ATPase (proton pump) on parietal cells, preventing the final step of acid secretion. This inhibition raises gastric pH, reduces overall acidity, and creates a less hostile environment for the esophageal mucosa, allowing damaged tissue to heal.

The appropriate dose of Pantoprazol Davur is determined by the prescribing clinician based on the specific indication, severity of disease, and patient characteristics. Healthcare professionals set the dosage and duration according to current clinical guidelines and individual patient needs.

Pantoprazole is classified as pregnancy category B in the EU, indicating no evidence of risk in animal studies and insufficient human data. It should be used during pregnancy or lactation only when clearly needed, after a careful risk‑benefit assessment by the treating physician.

To place an order, submit an enquiry on the Pantoprazol Davur product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Pantoprazol Davur belongs to the proton pump inhibitor class, which provides more potent and longer‑lasting acid suppression than H2‑receptor antagonists such as ranitidine. Compared with other PPIs, pantoprazole has a low potential for CYP‑mediated drug interactions, making it a suitable option for patients on multiple medications.

Store Pantoprazol Davur tablets at temperatures below 25 °C in their original packaging. Protect the product from moisture, excessive heat and direct sunlight to maintain potency throughout its shelf life.

Pantoprazol Davur is taken orally, usually as a whole tablet with a glass of water. It can be administered with or without food, but consistency in timing relative to meals helps maintain stable drug levels.

Serious adverse events, although rare, include severe allergic reactions, Clostridioides difficile‑associated diarrhoea, low magnesium levels, bone fractures with long‑term use, and acute interstitial nephritis. Patients should seek immediate medical attention if they experience symptoms such as rash, persistent diarrhoea, muscle cramps or reduced urine output.

Pantoprazol Davur is contraindicated in individuals with known hypersensitivity to pantoprazole or any other component of the formulation. Caution is also advised for patients with severe liver impairment, those taking certain interacting medications, and pregnant or breastfeeding women unless the benefit outweighs potential risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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