Product image of Pantoprazol Stada (Pantoprazole) supplied by GNH India

Pantoprazol Stada

Active Ingredient:
Pantoprazole
Origin:
EU

Pantoprazol Stada (Pantoprazole)

Pantoprazole, the active ingredient in Pantoprazol Stada, is a proton pump inhibitor presented as an oral tablet for oral use. It reduces gastric acid production and is indicated for conditions such as gastro‑oesophageal reflux disease, erosive oesophagitis and Zollinger‑Ellison syndrome in adult patients.
GNH India supplies Pantoprazol Stada as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Stada Arzneimittel Ag

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Indications & Clinical Uses

  • Pantoprazole is a proton pump inhibitor used to reduce gastric acid secretion in several acid‑related conditions.
  • Gastro‑oesophageal reflux disease (GERD): provides symptomatic relief and promotes healing of esophageal irritation.
  • Erosive oesophagitis: heals mucosal damage and prevents recurrence.
  • Zollinger‑Ellison syndrome: controls excessive gastric acid secretion.
  • Peptic ulcer disease: facilitates ulcer healing and reduces recurrence risk.

How It Works

  • Pantoprazole selectively and irreversibly binds to the H+/K+‑ATPase enzyme (the gastric proton pump) on the parietal cell surface, inhibiting the final step of acid secretion. By blocking this pump, it markedly reduces both basal and stimulated gastric acid output, allowing the gastrointestinal mucosa to heal and symptoms to improve.

Side Effects

Pantoprazole is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Diarrhoea: loose stools, usually transient.
  • Nausea: occasional feeling of queasiness.
  • Abdominal pain: mild discomfort in the stomach area.
  • Flatulence: increased gas production.
  • Constipation: reduced bowel movements.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction requiring immediate medical attention.
  • Clostridioides difficile infection: severe colitis presenting with watery diarrhoea.
  • Hypomagnesemia: low serum magnesium levels, potentially causing muscle cramps.
  • Elevated liver enzymes: signs of hepatic stress.
  • Stevens‑Johnson syndrome: rare skin disorder with blistering.
  • Acute pancreatitis: inflammation of the pancreas presenting with abdominal pain.

Precautions & Warnings

  • Before initiating therapy, consider patient‑specific factors and monitor for potential complications.
  • Assess renal function: dose adjustment may be needed in severe impairment.
  • Monitor magnesium levels: prolonged use can lead to hypomagnesemia.
  • Evaluate liver disease: use with caution in moderate to severe hepatic impairment.
  • Use caution in elderly patients: increased susceptibility to adverse effects.
  • Review concomitant medications: potential for drug‑drug interactions.
  • Store at room temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Pantoprazol Stada may affect the pharmacokinetics of several co‑administered drugs.

Major Interactions (Avoid)

  • Atazanavir (HIV protease inhibitor): reduced absorption and efficacy.
  • Clarithromycin (macrolide antibiotic): increased pantoprazole plasma concentrations.
  • Methotrexate (high‑dose): heightened toxicity risk.

Moderate Interactions (Monitor Closely)

  • Warfarin: possible increase in INR, requiring closer monitoring.
  • Diazepam: may raise serum levels, enhancing sedative effects.
  • Digoxin: potential increase in serum concentration, necessitating dose adjustment.

Frequently Asked Questions

Pantoprazol Stada contains pantoprazole, a proton pump inhibitor indicated for the treatment of gastro‑oesophageal reflux disease, erosive oesophagitis, Zollinger‑Ellison syndrome and for promoting healing of peptic ulcers. It works by reducing stomach acid, thereby relieving symptoms and allowing damaged mucosa to recover.

Pantoprazole blocks the H+/K+‑ATPase enzyme, also known as the gastric proton pump, located on the surface of parietal cells in the stomach. By irreversibly inhibiting this pump, it suppresses the final step of acid secretion, leading to a marked reduction in gastric acidity and facilitating mucosal healing.

The appropriate dose of Pantoprazol Stada is determined by the prescribing healthcare professional based on the specific indication, patient characteristics and clinical response. Dosage regimens may vary, and patients should follow the prescriber’s instructions without deviation.

Limited clinical data are available for pantoprazole use in pregnancy. It should only be prescribed if the potential benefit justifies any potential risk to the fetus. Pantoprazole is excreted in breast milk in small amounts; breastfeeding mothers should discuss risks and benefits with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity of Pantoprazol Stada. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials before providing pricing, availability, shipping details and necessary import documentation.

Pantoprazol Stada offers efficacy comparable to other proton pump inhibitors such as omeprazole or esomeprazole for acid‑related disorders. Differences may include drug‑interaction profiles, metabolism pathways and dosing convenience. Clinicians often select a specific PPI based on patient comorbidities, potential interactions and formulary considerations.

Store Pantoprazol Stada at room temperature, below 25 °C, in the original packaging to protect it from moisture and light. Keep the product out of reach of children and avoid storing it in humid environments such as bathrooms.

Pantoprazol Stada is taken orally as a tablet with a glass of water. It is usually administered once daily, preferably in the morning before a meal, unless otherwise directed by a healthcare professional.

Serious risks include severe allergic reactions such as anaphylaxis, Clostridioides difficile‑associated diarrhoea, low magnesium levels (hypomagnesemia), liver enzyme elevations and rare skin disorders like Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they experience symptoms such as rash, persistent diarrhoea, muscle cramps or signs of an allergic reaction.

Pantoprazol Stada should be avoided in individuals with known hypersensitivity to pantoprazole or any component of the formulation. Caution is also advised for patients with severe liver disease, and it is contraindicated in those with a history of severe allergic reactions to proton pump inhibitors.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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