Product image of Pantoprazol Teva (Pantoprazole) supplied by GNH India

Pantoprazol Teva

Active Ingredient:
Pantoprazole
Origin:
EU

Pantoprazol Teva (Pantoprazole)

Pantoprazole, the active ingredient in Pantoprazol Teva, is a proton pump inhibitor presented as a tablet for oral use. It reduces stomach acid production and is used to treat conditions such as gastro‑oesophageal reflux disease and peptic ulcer disease in adults.
GNH India supplies Pantoprazol Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva Nederland B.V.

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Indications & Clinical Uses

Pantoprazol Teva is a proton pump inhibitor that acts on the gastric acid secretion pathway. It is indicated for:

  • Gastro‑oesophageal reflux disease (GERD): improves symptom control and promotes healing of the oesophageal lining.
  • Erosive oesophagitis: accelerates healing of erosive lesions in the oesophagus.
  • Peptic ulcer disease: supports ulcer healing and reduces recurrence risk.

How It Works

  • Pantoprazole inhibits the H+/K+‑ATPase enzyme (the gastric proton pump) located on the secretory surface of parietal cells in the stomach. By binding irreversibly to this pump, it blocks the final step of acid secretion, leading to a sustained decrease in gastric acidity and an elevated gastric pH.

Side Effects

Pantoprazol Teva may cause a range of adverse reactions.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Diarrhoea: typically self‑limiting.
  • Nausea: occasional and transient.
  • Abdominal pain: mild discomfort.
  • Flatulence: increased intestinal gas.
  • Constipation: occasional bowel habit change.

Serious or Rare Side Effects

  • Severe allergic reaction: rash, itching, swelling, or difficulty breathing.
  • Clostridioides difficile infection: persistent watery diarrhoea.
  • Low magnesium levels (hypomagnesemia): muscle cramps, irregular heartbeat.
  • Fracture risk: reduced bone mineral density with long‑term use.
  • Liver enzyme elevation: signs of hepatic dysfunction.
  • Acute interstitial nephritis: kidney inflammation presenting with fever and flank pain.

Precautions & Warnings

When prescribing Pantoprazol Teva, consider the following precautions:

  • Assess renal function: adjust use in severe renal impairment.
  • Monitor magnesium levels: especially during prolonged therapy.
  • Evaluate bone health: consider calcium/vitamin D supplementation for long‑term users.
  • Review concomitant medications: potential for altered absorption of drugs requiring acidic pH.
  • Pregnancy and lactation: use only if clearly needed after risk‑benefit assessment.
  • Store at below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Pantoprazol Teva can interact with several medicines.

Major Interactions (Avoid)

  • Antifungal agents (ketoconazole, itraconazole): reduced absorption and efficacy.
  • HIV protease inhibitors (ritonavir, lopinavir): decreased plasma concentrations.
  • Clopidogrel: diminished antiplatelet effect, increasing cardiovascular risk.

Moderate Interactions (Monitor Closely)

  • Warfarin: potential alteration of INR values.
  • Methotrexate: increased serum levels, especially in renal impairment.
  • Digoxin: modest increase in serum concentration.
  • Oral contraceptives: possible reduction in hormonal efficacy.

Frequently Asked Questions

Pantoprazol Teva contains pantoprazole, a proton pump inhibitor that is prescribed to manage gastro‑oesophageal reflux disease, erosive oesophagitis and peptic ulcer disease. It works by lowering stomach acidity, which helps relieve symptoms, promotes healing of the gastrointestinal lining and reduces the risk of ulcer recurrence.

Pantoprazole blocks the H+/K+‑ATPase enzyme, also known as the gastric proton pump, on the surface of stomach parietal cells. By irreversibly inhibiting this pump, it stops the final step of acid production, leading to a sustained increase in gastric pH and decreased acidity.

The dosage of Pantoprazol Teva is determined by the prescribing clinician based on the patient’s specific condition, severity and response to therapy. The prescriber will set the appropriate strength, frequency and duration according to current clinical guidelines.

Pantoprazol Teva should be used in pregnancy or while breastfeeding only when clearly needed. The prescriber will weigh potential benefits against any risks to the fetus or infant, as limited data are available and safety cannot be guaranteed.

To place an order, submit an enquiry on the Pantoprazol Teva product page at gnhindia.com, providing the required quantity and your institutional details. GNH India works with hospitals, pharmacies and procurement teams worldwide, confirming trade or institutional credentials before replying with pricing, availability, shipping terms and any necessary import documentation.

Pantoprazol Teva is a proton pump inhibitor similar to omeprazole, esomeprazole and lansoprazole. All inhibit the gastric proton pump, but pantoprazole has a relatively stable chemical structure that is less affected by CYP2C19 metabolism, which can result in more consistent acid suppression in patients with certain genetic profiles.

Store Pantoprazol Teva tablets at temperatures below 25 °C in their original packaging. Protect the product from moisture, humidity and direct sunlight to maintain potency throughout its shelf life.

Pantoprazol Teva is supplied as oral tablets that are taken with water. It is usually administered once daily, preferably in the morning before a meal, unless the prescriber advises a different schedule based on the patient’s therapeutic needs.

Serious risks include severe allergic reactions, Clostridioides difficile‑associated diarrhoea, low magnesium levels, increased fracture risk with long‑term use, liver enzyme elevations and acute interstitial nephritis. Patients should seek immediate medical attention if they experience symptoms such as rash, persistent diarrhoea, muscle cramps or unexplained fatigue.

Pantoprazol Teva is contraindicated in individuals with known hypersensitivity to pantoprazole or any other components of the formulation. Caution is also advised for patients with severe liver impairment, those taking certain interacting medications, and anyone for whom acid suppression is medically inappropriate.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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