Product image of Paraceta 500 (Paracetamol) supplied by GNH India

Paraceta 500

Active Ingredient:
Paracetamol
Origin:
EU

Paraceta 500 (Paracetamol)

Paracetamol, the active ingredient in Paraceta 500, is an analgesic presented as a 500 mg tablet for oral use. It treats pain and fever in adults and children.

GNH India supplies Paraceta 500 as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Zentiva Pharma Gmbh

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Indications & Clinical Uses

  • Paracetamol is an analgesic and antipyretic that acts on the prostaglandin pathway to relieve symptoms.
  • Pain: reduces mild to moderate pain such as headache or muscle ache
  • Fever: lowers elevated body temperature
  • Headache: alleviates tension‑type headache
  • Dental pain: provides relief after dental procedures
  • Musculoskeletal pain: eases joint and back discomfort

How It Works

  • Paracetamol inhibits cyclooxygenase (COX) enzymes, primarily COX‑2, in the central nervous system, leading to decreased synthesis of prostaglandins that mediate pain and fever. This central action reduces the perception of pain and resets the hypothalamic temperature set‑point, producing antipyretic effects without significant peripheral anti‑inflammatory activity.

Side Effects

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea: mild stomach upset
  • Abdominal discomfort: mild pain or tenderness
  • Headache: transient sensation of pressure
  • Rash: mild skin irritation or erythema

Serious or Rare Side Effects

  • Stevens‑Johnson syndrome: severe skin and mucosal reaction
  • Hepatic failure: potential liver toxicity, especially with overdose
  • Anaphylaxis: rare severe allergic response requiring immediate medical attention

Precautions & Warnings

Paracetamol should be used with attention to individual health status.

  • Assess liver function: avoid in severe hepatic impairment
  • Avoid alcohol: concurrent use may increase risk of liver injury
  • Use lowest effective dose: limit total daily intake to 4 g
  • Monitor for allergic reactions: discontinue if rash or swelling develops
  • Store at ambient temperature: keep below 25°C in the original pack, protect from moisture

Avoid Interactions

Paracetamol may interact with several medicines; review patient medication lists.

Major Interactions (Avoid)

  • Alcohol: increased risk of hepatotoxicity
  • Warfarin: enhanced anticoagulant effect, may require INR monitoring
  • Carbamazepine: reduced analgesic efficacy of paracetamol

Moderate Interactions (Monitor Closely)

  • Isoniazid: potential elevation of liver enzymes
  • Phenytoin: may increase metabolism of paracetamol, reducing its effect

Frequently Asked Questions

Paraceta 500 contains paracetamol and is used to relieve mild to moderate pain such as headache, toothache, muscle aches, and to reduce fever. It is an over‑the‑counter option for adults and children when a non‑opioid analgesic is appropriate.

Paracetamol works by inhibiting cyclooxygenase enzymes in the central nervous system, which lowers the production of prostaglandins that signal pain and regulate body temperature. This central action reduces the perception of pain and helps reset the hypothalamic set‑point for fever.

The specific dose of Paraceta 500 is determined by the prescribing healthcare professional based on the patient’s age, weight, and clinical condition. In practice, the total daily amount of paracetamol should not exceed 4 grams for most adults, but exact dosing must follow the prescriber’s instructions.

Safety data for paracetamol in pregnancy and lactation are limited, and the product does not have an established pregnancy category. Women who are pregnant, planning to become pregnant, or breastfeeding should consult their physician before using Paraceta 500 to weigh potential benefits against risks.

To place an order, submit an enquiry on the Paraceta 500 product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Paraceta 500 (paracetamol) provides analgesic and antipyretic effects without significant anti‑inflammatory activity, whereas ibuprofen is a non‑steroidal anti‑inflammatory drug (NSAID) that also reduces inflammation. Paracetamol is generally gentler on the stomach and does not affect platelet function, but ibuprofen may be preferred when inflammation is a major component of pain.

Paraceta 500 tablets should be stored at ambient temperature, preferably below 25 °C, in their original packaging to protect them from moisture and light. Keep the product out of reach of children and avoid storing in humid or excessively hot environments.

Paraceta 500 is taken orally with a glass of water. The tablet can be swallowed whole and may be taken with or without food, according to the prescriber’s guidance. Patients should follow the dosing schedule provided by their healthcare professional.

The most serious risks include severe liver injury, especially with overdose or chronic high‑dose use, and rare allergic reactions such as Stevens‑Johnson syndrome or anaphylaxis. Any signs of jaundice, unusual fatigue, rash, or swelling should prompt immediate medical evaluation.

Paraceta 500 should be avoided by individuals with known hypersensitivity to paracetamol, severe liver disease, or those who regularly consume excessive alcohol. It is also contraindicated in patients who are taking other paracetamol‑containing products that could lead to exceeding the maximum daily dose.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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