Product image of Paracetalgin (Paracetamol) supplied by GNH India

Paracetalgin

Active Ingredient:
Paracetamol
Origin:
EU

Paracetalgin (Paracetamol)

Paracetamol, the active ingredient in Paracetalgin, is an analgesic presented as an oral formulation for oral use. It is used to relieve mild to moderate pain and reduce fever in adults and children when appropriate. It works by inhibiting cyclooxygenase enzymes, decreasing prostaglandin synthesis in the central nervous system.

GNH India supplies Paracetalgin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, clinics and procurement teams worldwide.

Manufacturer / TM Owner

Teva B.V

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Indications & Clinical Uses

Paracetamol is an analgesic that reduces pain and fever by acting on the prostaglandin pathway.

  • Pain: Provides relief from mild to moderate pain such as headache, muscle aches, or dental discomfort.
  • Fever: Lowers elevated body temperature associated with infections or inflammatory conditions.
  • Cold and flu symptoms: Alleviates discomfort and fever commonly experienced during viral upper respiratory infections.

How It Works

  • Paracetamol exerts its analgesic and antipyretic actions primarily through inhibition of cyclooxygenase (COX) enzymes in the central nervous system, leading to reduced synthesis of prostaglandins that mediate pain and fever. The drug’s weak peripheral anti‑inflammatory activity reflects its limited effect on COX enzymes outside the brain and spinal cord.

Side Effects

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea: Mild stomach upset may be experienced.
  • Headache: Some users report transient head discomfort.
  • Dizziness: Light‑headedness can occur, especially with rapid dosing.
  • Skin rash: Mild itching or rash may develop.

Serious or Rare Side Effects

  • Liver toxicity: Elevated liver enzymes or hepatic failure, particularly with overdose.
  • Severe allergic reactions: Anaphylaxis, angioedema, or bronchospasm.
  • Stevens‑Johnson syndrome: Rare but serious skin disorder.
  • Blood disorders: Neutropenia or thrombocytopenia in uncommon cases.

Precautions & Warnings

When using Paracetalgin, consider the following safety measures.

  • Assess liver function: Avoid in patients with severe hepatic impairment.
  • Limit alcohol intake: Excessive alcohol increases risk of liver injury.
  • Monitor pediatric dosing: Follow age‑appropriate dosing guidelines.
  • Review concomitant medications: Check for interactions with anticoagulants, anticonvulsants, and other hepatotoxic drugs.
  • Store at ambient temperature: Keep in the original container, protect from moisture and heat.

Avoid Interactions

Paracetalgin may interact with several medicines; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Warfarin: Enhanced anticoagulant effect may increase bleeding risk.
  • Isoniazid: Combined use raises potential for liver toxicity.
  • Carbamazepine: May reduce the analgesic efficacy of paracetamol.
  • Phenobarbital: Increases risk of hepatotoxicity when co‑administered.

Moderate Interactions (Monitor Closely)

  • Alcohol: Adds to hepatic strain and may potentiate toxicity.
  • Other hepatotoxic agents (e.g., valproate): Cumulative liver stress.
  • Anticonvulsants such as phenytoin: May alter paracetamol metabolism.
  • Oral contraceptives: Slightly increased risk of liver enzyme elevation.

Frequently Asked Questions

Paracetalgin contains paracetamol, an analgesic and antipyretic used to relieve mild to moderate pain such as headaches, muscle aches, dental pain, and to lower fever associated with infections or inflammatory conditions. It is commonly employed in both adult and pediatric populations when a non‑opioid option is appropriate.

Paracetamol works by inhibiting cyclooxygenase enzymes in the central nervous system, which reduces the production of prostaglandins—chemical mediators that signal pain and fever. This central action provides analgesic and antipyretic effects while having minimal anti‑inflammatory activity in peripheral tissues.

The appropriate dose of Paracetalgin is determined by a qualified prescriber based on the patient’s age, weight, clinical condition, and any relevant medical history. Dosage instructions are individualized and should follow the healthcare professional’s recommendation and local regulatory guidelines.

Paracetamol is generally considered the analgesic of choice during pregnancy and lactation when needed, but safety depends on the specific clinical situation. Pregnant or nursing individuals should consult their healthcare provider before using Paracetalgin to ensure appropriate risk‑benefit assessment.

To place an order, submit an enquiry on the Paracetalgin product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Paracetalgin (paracetamol) differs from non‑steroidal anti‑inflammatory drugs (NSAIDs) such as ibuprofen in that it has minimal peripheral anti‑inflammatory activity and a lower risk of gastrointestinal irritation. It is also less likely to affect platelet function, making it a preferred option when NSAID‑related side effects are a concern.

Paracetalgin should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture, direct sunlight, and excessive heat to maintain its stability and potency throughout its shelf life.

Paracetalgin is administered orally. The tablet or liquid is swallowed with water, following the dose prescribed by a healthcare professional. It should be taken with or without food, according to the prescriber’s guidance, and the full prescribed course should be completed unless otherwise advised.

The most serious risks include liver toxicity, especially with overdose or chronic high‑dose use, and severe allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome. Patients should be monitored for signs of hepatic dysfunction (e.g., jaundice, dark urine) and any unexpected skin or respiratory symptoms.

Paracetalgin should be avoided in individuals with known hypersensitivity to paracetamol or any of its excipients, in patients with severe hepatic impairment, and in those who have experienced serious adverse reactions such as liver failure or severe skin reactions from previous paracetamol use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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