Product image of Paracetamol 1000mg Tablets (Paracetamol Ph. Eur.) supplied by GNH India

Paracetamol 1000mg Tablets

Active Ingredient:
Paracetamol Ph. Eur.
Origin:
EU

Paracetamol 1000mg Tablets (Paracetamol Ph. Eur.)

Paracetamol, the active ingredient in Paracetamol 1000mg Tablets, is an analgesic presented as a 1000 mg tablet for oral use. It treats pain and fever in adults and children when appropriate dosing is applied.

GNH India supplies Paracetamol 1000mg Tablets as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Noumed Life Sciences

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Indications & Clinical Uses

Paracetamol is an analgesic and antipyretic that acts on common pain‑related pathways and fever mechanisms.

  • Headache: provides relief of mild to moderate headache pain.
  • Musculoskeletal pain: reduces discomfort from strains, sprains and low‑back pain.
  • Fever: lowers elevated body temperature associated with infection or inflammation.

How It Works

  • Paracetamol inhibits the synthesis of prostaglandins in the central nervous system, primarily by acting on the cyclooxygenase (COX) pathway. This reduction in prostaglandin levels diminishes pain signalling and lowers the hypothalamic set‑point for temperature regulation, producing analgesic and antipyretic effects.

Side Effects

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea: mild stomach upset may be reported.
  • Skin rash: occasional mild dermatologic reaction.
  • Elevated liver enzymes: transient increase in laboratory values.

Serious or Rare Side Effects

  • Hepatotoxicity: risk of liver injury with overdose or chronic high‑dose use.
  • Stevens‑Johnson syndrome: rare severe skin reaction.
  • Anaphylaxis: extremely rare systemic allergic response.
  • Blood disorders: rare cases of thrombocytopenia or neutropenia.

Precautions & Warnings

Paracetamol should be used with awareness of specific safety considerations.

  • Dose limits: do not exceed the maximum daily amount recommended by a healthcare professional.
  • Liver disease: avoid use or adjust dose in patients with existing hepatic impairment.
  • Alcohol use: limit alcohol consumption while taking this medication.
  • Pregnancy and breastfeeding: consult a healthcare provider before use.
  • Store below 25°C: keep in the original packaging, protect from moisture and heat.

Avoid Interactions

Paracetamol may interact with several medicines, requiring attention to avoid reduced efficacy or increased toxicity.

Major Interactions (Avoid)

  • Warfarin: may enhance anticoagulant effect and increase bleeding risk.
  • Isoniazid: can raise risk of liver toxicity.

Moderate Interactions (Monitor Closely)

  • Antiepileptics (e.g., carbamazepine, phenytoin): may increase metabolism of paracetamol, lowering its effectiveness.
  • Rifampicin: may reduce plasma concentrations of paracetamol.
  • Oral contraceptives: may slightly increase hepatic metabolism of paracetamol.

Frequently Asked Questions

Paracetamol 1000mg Tablets are used to relieve mild to moderate pain such as headache, muscle aches, and to reduce fever. The tablet provides a high‑strength dose suitable for adults when a prescriber determines that a 1000 mg strength is appropriate for the individual’s clinical need.

Paracetamol works by inhibiting prostaglandin synthesis in the central nervous system, which reduces pain signalling and lowers the hypothalamic set‑point for body temperature. This dual action provides both analgesic and antipyretic effects without significant anti‑inflammatory activity.

The dose is set by a qualified prescriber based on the patient’s age, weight, medical condition and other medications. Healthcare professionals determine the appropriate frequency and total daily amount, ensuring it does not exceed recommended safety limits.

Paracetamol is classified as a drug with limited pregnancy data; it should only be used during pregnancy or while breastfeeding when a healthcare professional has evaluated the benefit‑risk balance. Consultation with a prescriber is essential before use.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and import documentation.

Paracetamol provides analgesic and antipyretic effects without the anti‑inflammatory activity of NSAIDs such as ibuprofen. It is generally gentler on the stomach and does not affect platelet function, but it lacks the anti‑inflammatory benefits and carries a higher risk of liver toxicity at excessive doses.

Store the tablets below 25 °C in their original packaging, protecting them from moisture, heat and direct sunlight. Proper storage helps maintain tablet potency and prevents degradation.

The tablets are intended for oral use. They should be swallowed whole with water and not chewed or crushed, unless a prescriber specifically advises an alternative method of administration.

The most serious risk is hepatotoxicity, which can occur with overdose or chronic high‑dose use, potentially leading to liver failure. Rare severe skin reactions such as Stevens‑Johnson syndrome and anaphylaxis have also been reported.

Individuals with known severe liver disease, hypersensitivity to paracetamol, or those taking interacting medicines that increase liver risk should avoid this product unless a prescriber determines it is safe. Pregnant or breastfeeding women should only use it under medical guidance.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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