Product image of Paracetamol supplied by GNH India

Paracetamol

Active Ingredient:
Paracetamol
Origin:
EU

Paracetamol

Paracetamol, the active ingredient in Paracetamol, is an Analgesic presented as a tablet for oral use. It relieves mild to moderate pain and reduces fever in adults and children, providing symptomatic relief for common ailments such as headache, musculoskeletal discomfort, and febrile conditions.

GNH India supplies Paracetamol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The product meets EU quality standards and is manufactured under strict Good Manufacturing Practice guidelines. It is distributed through a secure logistics network to ensure product integrity.

Manufacturer / TM Owner

Ionfarma S.L.U.

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Indications & Clinical Uses

Paracetamol is used to manage pain and fever across several common conditions.

  • Headache: reduces pain associated with tension‑type headaches.
  • Fever: lowers elevated body temperature in febrile conditions.
  • Musculoskeletal pain: alleviates mild to moderate pain from strains or sprains.
  • Dental pain: provides analgesia for toothache and post‑extraction discomfort.

How It Works

  • Paracetamol acts centrally by inhibiting the cyclooxygenase (COX) enzymes, primarily COX‑2, within the brain and spinal cord. This reduces the synthesis of prostaglandins involved in pain perception and thermoregulation, leading to analgesic and antipyretic effects without significant peripheral anti‑inflammatory activity.

Side Effects

Paracetamol may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Nausea: mild stomach upset that usually resolves without intervention.
  • Rash: skin irritation or mild erythema.
  • Abdominal discomfort: transient stomach pain or indigestion.
  • Dizziness: occasional light‑headedness.
  • Sweating: increased perspiration.
  • Elevated liver enzymes: laboratory finding without clinical symptoms.

Serious or Rare Side Effects

  • Hepatotoxicity: severe liver injury, especially with overdose.
  • Stevens‑Johnson syndrome: rare, life‑threatening skin reaction.
  • Blood dyscrasias: such as agranulocytosis or thrombocytopenia.
  • Anaphylactic reaction: immediate hypersensitivity requiring emergency care.

Precautions & Warnings

When using paracetamol, consider the following safety measures.

  • Liver function: avoid use in patients with severe hepatic impairment.
  • Alcohol consumption: limit intake as combined use increases hepatotoxic risk.
  • Pregnancy: use only under medical advice, especially in the third trimester.
  • Drug interactions: review all concomitant medications for potential conflicts.
  • Age considerations: dose adjustments may be required for children and the elderly.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Paracetamol can interact with other medicines; notable interactions include:

Major Interactions (Avoid)

  • Warfarin: may increase anticoagulant effect and risk of bleeding.
  • Isoniazid: heightened risk of liver injury when combined.

Moderate Interactions (Monitor Closely)

  • Alcohol: additive hepatotoxic potential.
  • Carbamazepine: may reduce paracetamol efficacy.
  • Phenobarbital: can increase paracetamol metabolism, lowering its effectiveness.

Frequently Asked Questions

Paracetamol is an analgesic and antipyretic medication used to relieve mild to moderate pain such as headache, toothache, muscle aches, and to reduce fever associated with infections or inflammatory conditions.

Paracetamol works by inhibiting central cyclooxygenase enzymes, mainly COX‑2, which lowers the production of prostaglandins in the brain and spinal cord. This action reduces the perception of pain and helps reset the body’s temperature set‑point, producing antipyretic effects.

The appropriate dose of paracetamol is set by a prescriber based on the patient’s age, weight, clinical condition, and any existing liver or kidney impairment. Standard adult dosing typically ranges from 500 mg to 1 g per dose, but exact regimens must follow the healthcare professional’s instructions.

Paracetamol is generally considered safe for short‑term use during pregnancy and lactation when prescribed by a healthcare professional. However, it should be used at the lowest effective dose and only when clearly indicated, as individual risk factors must be evaluated by the treating clinician.

To order paracetamol, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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