Product image of Paracetamol supplied by GNH India

Paracetamol

Active Ingredient:
Paracetamol
Origin:
EU

Paracetamol

Paracetamol, the active ingredient in Paracetamol, is an analgesic presented as an unknown/unknown for oral use. It treats pain and fever in adults and children, providing relief for common mild to moderate discomfort.\n\nGNH India supplies Paracetamol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Crescent Pharma Limited

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Indications & Clinical Uses

  • Paracetamol acts as a centrally acting analgesic and antipyretic, reducing pain and fever across several common conditions.\n\n- Fever: Lowers elevated body temperature.\n- Headache: Relieves tension‑type and mild migraine pain.\n- Musculoskeletal pain: Alleviates aches from strains or over‑use.\n- Toothache: Reduces dental pain after procedures.\n- Cold and flu symptoms: Eases associated mild pain and fever.

How It Works

  • Paracetamol exerts its effect primarily by inhibiting cyclooxygenase enzymes (COX‑1 and COX‑2) in the central nervous system, leading to decreased synthesis of prostaglandins that mediate pain and fever. Its action is largely peripheral‑independent, providing antipyretic and analgesic activity without significant anti‑inflammatory effects.

Side Effects

  • Paracetamol is generally well tolerated, but adverse reactions can occur.\n\nCommon Side Effects:\n- Nausea\n- Skin rash or mild itching\n- Dizziness\n- Upper abdominal discomfort\n- Elevated liver enzymes (asymptomatic)\n\nSerious or Rare Side Effects:\n- Stevens‑Johnson syndrome or toxic epidermal necrolysis\n- Acute liver failure, especially with overdose\n- Blood dyscrasias such as agranulocytosis\n- Anaphylactic or anaphylactoid reactions\n- Severe skin reactions including drug reaction with eosinophilia and systemic symptoms (DRESS).

Precautions & Warnings

  • Paracetamol should be used with awareness of specific safety considerations.\n\n- Pregnancy: Use only when clearly needed and after medical advice.\n- Liver disease: Avoid or limit use; monitor hepatic function.\n- Alcohol consumption: Limit intake to reduce hepatotoxic risk.\n- Children: Ensure appropriate formulation and dosing by a healthcare professional.\n- Concomitant use with other paracetamol‑containing products: Avoid duplicate therapy.\n- Store at ambient temperature: Keep below 25°C, in the original packaging, protected from moisture and direct sunlight.

Avoid Interactions

  • Paracetamol can interact with several medicines, requiring attention to dosage and monitoring.\n\nMajor Interactions (Avoid):\n- Warfarin: May increase anticoagulant effect and bleeding risk.\n- Alcohol: Heightens risk of liver injury.\n- Carbamazepine: May reduce paracetamol plasma levels.\n\nModerate Interactions (Monitor Closely):\n- Isoniazid: Potential for increased hepatotoxicity.\n- Phenobarbital: May enhance hepatic metabolism of paracetamol.\n- Oral contraceptives: May slightly increase hepatic enzyme activity, requiring monitoring.

Frequently Asked Questions

Paracetamol is used to relieve mild to moderate pain such as headache, toothache, muscle aches, and to reduce fever associated with common infections or inflammatory conditions. It is a first‑line option for many over‑the‑counter pain‑relief needs.

Paracetamol works by inhibiting central cyclooxygenase enzymes, which reduces the production of prostaglandins that signal pain and raise body temperature. This central action provides analgesic and antipyretic effects without significant anti‑inflammatory activity.

The appropriate dose of Paracetamol is determined by a prescriber or according to the product label, based on the patient’s age, weight, and clinical condition. Dosage instructions should always be followed as directed by a healthcare professional.

Paracetamol is generally considered safe for short‑term use during pregnancy and lactation when used at recommended doses. However, it should only be taken when clearly needed and under the guidance of a qualified healthcare provider.

To order Paracetamol, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Paracetamol provides analgesic and antipyretic effects without the anti‑inflammatory activity of ibuprofen. It is gentler on the stomach and does not affect platelet function, making it preferable for patients who need pain relief but cannot tolerate NSAIDs.

Paracetamol should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Paracetamol is administered orally, typically as tablets, capsules, or liquid formulations. It should be taken with or without food, according to the prescribing information, and the dose should be spaced appropriately to avoid exceeding the daily maximum.

The most serious risks include severe liver injury, especially with overdose or chronic high‑dose use, and rare hypersensitivity reactions such as Stevens‑Johnson syndrome. Prompt medical attention is required if signs of liver dysfunction or severe skin reactions appear.

Paracetamol should be avoided by individuals with known hypersensitivity to the drug, severe liver disease, or those who are regularly consuming high amounts of alcohol. Children under the recommended age or weight limits should not use adult formulations without professional guidance.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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